Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | SREBF2 | Q12772 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9271730 | 0.98 | RAB9A (0.55) | RAB9AGAAPOLBNPC1KDM4E | |
| SCHEMBL17130336 | 0.84 | RAB9A (0.58) | RAB9AGAAPOLBNPC1KDM4E | |
| SCHEMBL2706140 | 0.82 | GFER (0.72) | RAB9AGAAPOLBNPC1KDM4E | |
| SCHEMBL2056124 | 0.82 | GFER (0.72) | RAB9AGAAPOLBNPC1KDM4E | |
| SCHEMBL2225013 | 0.82 | LMNA (0.62) | RAB9AGAAPOLBNPC1KDM4E | |
| SCHEMBL153338 | 0.81 | HPGD (0.60) | RAB9AGAAPOLBNPC1KDM4E | |
| SCHEMBL6760692 | 0.81 | RAB9A (0.56) | RAB9AGAAPOLBNPC1KDM4E | |
| SCHEMBL16603157 | 0.81 | RAB9A (0.53) | RAB9AGAAPOLBNPC1KDM4E | |
| Hydrochloric Acid SCHEMBL17261462 | 0.80 | HPGD (0.59) | RAB9AGAAPOLBNPC1KDM4E | |
| SCHEMBL533107 | 0.79 | RAB9A (0.53) | RAB9AGAAPOLBNPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1037268-C | Antipicornaviral pyridazinamines | JANSSEM PHARMACEUTICA N V (BE) | 1998-02-04 | — | — | CN | disclosed |