Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6410586 | 1.00 | ALDH1A1 (0.46) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3928365 | 0.89 | MEN1 (0.40) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6408099 | 0.82 | ALDH1A1 (0.45) | ALDH1A1TSHRSMN1; SMN2CHRM5CHRM1 | |
| SCHEMBL6408133 | 0.81 | ALDH1A1 (0.44) | ALDH1A1ACHEFAAHKDM4EMAPK1 | |
| SCHEMBL6409457 | 0.81 | ALDH1A1 (0.47) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6416662 | 0.81 | ALDH1A1 (0.47) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6936484 | 0.79 | FAAH (0.44) | ALDH1A1LMNAACHEFAAHKDM4E | |
| SCHEMBL6410018 | 0.79 | FAAH (0.44) | ALDH1A1LMNAACHEFAAHKDM4E | |
| SCHEMBL4103973 | 0.78 | MEN1 (0.37) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL4095312 | 0.78 | MEN1 (0.37) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050249692-A1 | Polymer, cosmetic composition comprising same and method of preparing same | MITSUBISHI CHEMICAL CORPORATION | 2005-11-10 | — | — | US | disclosed |
| EP-1462463-A1 | Guanidin-group containing polymer, cosmetic employing same and method of preparing same | Mitsubishi Chemical Corporation (JP) | 2004-09-29 | — | — | EP | disclosed |
| EP-0805674-B1 | SKIN AND HAIR COSMETIC COMPOSITIONS | KAO CORP (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-20020172655-A1 | Cosmetic-use polymer, cosmetic employing same, and method of preparing same | MITSUBISHI CHEMICAL CORPORATION | 2002-11-21 | — | — | US | disclosed |
| EP-1236744-A2 | Guanidin-group containing polymer, cosmetic employing same and method of preparing same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6348200-B1 | OXYALKYLAMIDE OR AMINE DERIVATIVES;AT LEAST ONE OF POLYHYDRIC ALCOHOLS, OR VEGETABLE EXTRACTS, OR ORGANIC ACIDS; IMPROVES WATER-RETAINING ABILITY OF HORNY LAYER, CURES ROUGHNESS AND PREVENTS WRINKLES | KAO CORPORATION (JP) | 2002-02-19 | — | — | US | disclosed |
| US-6187955-B1 | A MOISTURIZER FOR SOFTENING SKINS; USEFUL AS COMPONENTS OF COSMETIC FORMULATIONS | KAO CORPORATION (JP) | 2001-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020172655-A1 | Cosmetic-use polymer, cosmetic employing same, and method of preparing same | DNMT1, PRMT1, JMJD6 | ALDH1A1 537/4885TSHR 3024/4885MEN1 317/4885 |
| US-20050249692-A1 | Polymer, cosmetic composition comprising same and method of preparing same | DNMT1, TET2, H1-0 | ALDH1A1 1198/4885TSHR 2711/4885MEN1 390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.