Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27799609 | 0.94 | ALDH1A1 (0.37) | ALDH1A1CA12CA14CA1CA7 | |
| SCHEMBL28300235 | 0.91 | ALDH1A1 (0.34) | ALDH1A1CA12CA14CA1CA7 | |
| SCHEMBL14604888 | 0.88 | HAO1 (0.41) | ALDH1A1CA12CA14CA1CA7 | |
| SCHEMBL1563570 | 0.86 | HAO1 (0.48) | ALDH1A1CES2CES1TSHR | |
| SCHEMBL1562138 | 0.84 | HAO1 (0.52) | ALDH1A1CES2CES1TSHR | |
| SCHEMBL29022869 | 0.84 | HAO1 (0.52) | ALDH1A1CES2CES1TSHR | |
| SCHEMBL10799382 | 0.84 | HAO1 (0.52) | ALDH1A1CES2CES1TSHR | |
| SCHEMBL1562098 | 0.84 | HAO1 (0.52) | ALDH1A1CES2CES1TSHR | |
| SCHEMBL10595444 | 0.84 | HAO1 (0.52) | ALDH1A1CES2CES1TSHR | |
| SCHEMBL2648388 | 0.84 | DGAT1 (0.42) | CA12CA14CA1CA7DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651424-A | A kind of simple synthesis of 7- protecting group -4- (1- hydrogen-pyrazoles -4- base) pyrroles [2,3-d] pyrimidine | 新发药业有限公司 | 2019-04-19 | — | — | CN | claimed |
| CN-108569949-A | A kind of synthesis 2- hydroxyls -2-（Containing methyl fluoride）The method of propionic acid | 北京艾德旺科技发展有限公司 | 2018-09-25 | — | — | CN | claimed |
| CN-106661395-B | Workpiece fixing sheet with resin layer | 琳得科株式会社 | 2021-05-28 | — | — | CN | disclosed |
| CN-106170489-B | New Pyrazolopyrimidine derivative and its purposes as MALT1 inhibitor | 诺华股份有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-109651955-A | A kind of preparation method based on acetoacetate-modified castor oil solidify coating | 江西科技师范大学 | 2019-04-19 | — | — | CN | disclosed |
| CN-109651424-A | A kind of simple synthesis of 7- protecting group -4- (1- hydrogen-pyrazoles -4- base) pyrroles [2,3-d] pyrimidine | 新发药业有限公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-108467613-A | Opaque aqueous UV damage resistant coatings | 威士伯采购公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-108142935-A | A kind of slimming capsule that natural polymer subbase gel inner nuclear material is controllably constructed based on dynamic chemical key | 上海市第十人民医院 | 2018-06-12 | — | — | CN | disclosed |
| CN-107814778-A | A kind of α acetyl group gamma butyrolactone continuous stream microchannel plate answers production technology | 南通醋酸化工股份有限公司 | 2018-03-20 | — | — | CN | disclosed |
| CN-105622961-B | A kind of preparation method of self-healing property polysaccharide hydrogel | 东华大学 | 2018-02-23 | — | — | CN | disclosed |
| CN-107431096-A | Rectifier cell, its manufacture method and radio communication device | 东丽株式会社 | 2017-12-01 | — | — | CN | disclosed |
| US-20040106808-A1 | Processes for preparing calanolide a and intermediates thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2004-06-03 | — | — | US | disclosed |
| EP-1352907-A1 | PROCESSES FOR PREPARING CALANOLIDE A AND INTERMEDIATES THEREOF | KURARAY CO., LTD. (JP) | 2003-10-15 | — | — | EP | disclosed |
| WO-2003035616-A2 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2003-05-01 | — | — | WO | disclosed |
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |
| EP-0418175-B1 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-07-17 | — | — | EP | disclosed |
| EP-0418175-A2 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1991-03-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106808-A1 | Processes for preparing calanolide a and intermediates thereof | CALR, CYP51A1, CYP4A11 | ALDH1A1 1043/4885CA12 245/4885CA14 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.