Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6225424 | 0.86 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1TDP1SMN1; SMN2KDM4E | |
| SCHEMBL6226222 | 0.81 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1TDP1SMN1; SMN2KDM4E | |
| SCHEMBL6415273 | 0.80 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1TDP1SMN1; SMN2KDM4E | |
| SCHEMBL13310655 | 0.80 | DRD2 (0.53) | ALDH1A1L3MBTL1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL6203530 | 0.79 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1TDP1SMN1; SMN2KDM4E | |
| SCHEMBL13615819 | 0.77 | IDH1 (0.46) | KDM4ENPC1RAB9ACSNK2A2CSNK2B | |
| SCHEMBL6415421 | 0.76 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1TDP1SMN1; SMN2KDM4E | |
| SCHEMBL6204839 | 0.76 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1TDP1SMN1; SMN2KDM4E | |
| SCHEMBL12862618 | 0.75 | PDE10A (0.58) | ALDH1A1L3MBTL1TDP1SMN1; SMN2KDM4E | |
| SCHEMBL6229232 | 0.75 | KDM4E (0.60) | ALDH1A1SMN1; SMN2KDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050277676-A1 | M3muscarinic acetylcholine receptor antagonists | GLAXO GROUP LIMITED (GB) | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277676-A1 | M3muscarinic acetylcholine receptor antagonists | CHRM3, CHRM2, CHRM5 | ALDH1A1 2606/4885L3MBTL1 837/4885TDP1 3534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.