Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | PIP4K2B | P78356 | 2/20 | 0.56 |
| ▸ | MRE11 | P49959 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6415604 | 1.00 | GSK3B (0.74) | GSK3BGAAL3MBTL1MAPTTDP1 | |
| SCHEMBL23094695 | 0.85 | GSK3B (1.00) | GSK3BGAAL3MBTL1MAPTTDP1 | |
| SCHEMBL8307311 | 0.82 | GSK3B (0.74) | GSK3BGAAL3MBTL1MAPTTDP1 | |
| SCHEMBL8307310 | 0.82 | GSK3B (0.74) | GSK3BGAAL3MBTL1MAPTTDP1 | |
| SCHEMBL23094478 | 0.81 | CISD1 (0.73) | GSK3BTDP1MEN1KMT2APOLB | |
| SCHEMBL22971852 | 0.81 | XDH (0.75) | GSK3BGAAMAPTTDP1MEN1 | |
| SCHEMBL8186384 | 0.73 | AKR1B1 (0.74) | GSK3BL3MBTL1MAPTTDP1MEN1 | |
| SCHEMBL14860974 | 0.73 | TDP1 (1.00) | GSK3BGAAL3MBTL1MAPTTDP1 | |
| SCHEMBL14860978 | 0.73 | TDP1 (1.00) | GSK3BGAAL3MBTL1MAPTTDP1 | |
| SCHEMBL8186386 | 0.73 | AKR1B1 (0.74) | GSK3BL3MBTL1MAPTTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050019825-A9 | Common ligand mimics: pseudothiohydantoins | TRIAD THERAPEUTICS, INC. | 2005-01-27 | — | — | US | disclosed |
| US-20040009527-A1 | Common ligand mimics: pseudothiohydantoins | DONG QING (US) | 2004-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050019825-A9 | Common ligand mimics: pseudothiohydantoins | FGFR3, BID, FLT3 | GSK3B 3537/4885GAA 4496/4885L3MBTL1 2681/4885 |
| US-20040009527-A1 | Common ligand mimics: pseudothiohydantoins | FGFR3, BID, FLT3 | GSK3B 3537/4885GAA 4496/4885L3MBTL1 2681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.