Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | PHGDH | O43175 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.42 |
| ▸ | INSR | P06213 | 2/20 | 0.42 |
| ▸ | RET | P07949 | 2/20 | 0.42 |
| ▸ | ROS1 | P08922 | 2/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.42 |
| ▸ | LTK | P29376 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | MERTK | Q12866 | 2/20 | 0.42 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2311758 | 0.77 | PHGDH (0.45) | PHGDHEGFRKDM4EMEN1ALDH1A1 | |
| SCHEMBL2306529 | 0.77 | PHGDH (0.45) | PHGDHEGFRKDM4EMEN1ALDH1A1 | |
| SCHEMBL17664356 | 0.73 | S1PR3 (0.62) | S1PR3 | |
| SCHEMBL18434128 | 0.71 | MEN1 (0.50) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL15870578 | 0.71 | CCNC (0.62) | CCNCCDK8EGFRABL1ERBB2 | |
| SCHEMBL11266049 | 0.70 | NPC1 (0.48) | CCNCCDK8PHGDHEGFRMEN1 | |
| SCHEMBL5208152 | 0.70 | CCNC (0.61) | CCNCCDK8RETSRCKDR | |
| SCHEMBL5820529 | 0.70 | CCNC (0.61) | CCNCCDK8RETSRCKDR | |
| SCHEMBL5820533 | 0.70 | CCNC (0.61) | CCNCCDK8RETSRCKDR | |
| SCHEMBL3228804 | 0.69 | CCNC (0.52) | CCNCCDK8EGFRKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050256150-A1 | Enantioselective acyl transfer catalysts and their use in kinetic resolution of alcohols and desymmetrization of meso-diols | WASHINGTON UNIVERSITY | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256150-A1 | Enantioselective acyl transfer catalysts and their use in kinetic resolution of alcohols and desymmetrization of meso-diols | ADH5, DBI, ADH1A | CCNC 3274/4885CDK8 3083/4885PHGDH 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.