Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6419765 | 0.90 | PIK3CD (0.32) | PIK3CDENPP1 | |
| SCHEMBL6415993 | 0.87 | ENPP1 (0.30) | PIK3CDENPP1 | |
| SCHEMBL6414196 | 0.87 | ENPP1 (0.30) | PIK3CDENPP1 | |
| SCHEMBL6413611 | 0.77 | ENPP1 (0.31) | PIK3CDENPP1 | |
| SCHEMBL6415728 | 0.74 | KDM4E (0.33) | PIK3CDENPP1 | |
| SCHEMBL6418941 | 0.73 | ENPP1 (0.34) | ENPP1 | |
| SCHEMBL6417723 | 0.68 | CFD (0.34) | ENPP1 | |
| SCHEMBL6417552 | 0.66 | ALDH1A1 (0.35) | PIK3CD | |
| SCHEMBL6418942 | 0.66 | ENPP1 (0.33) | PIK3CDENPP1 | |
| SCHEMBL5913952 | 0.65 | SMN1; SMN2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288502-A1 | Substituted heterocyclic compounds and methods of use | AMGEN, INC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288502-A1 | Substituted heterocyclic compounds and methods of use | MYLK2, IAPP, MAPT | PIK3CD 2182/4885RIPK1 35/4885ENPP1 1881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.