Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 5/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6413439 | 0.98 | LMNA (0.50) | LMNAKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL26034950 | 0.92 | KMT2A (0.58) | LMNAKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL12858715 | 0.75 | LMNA (0.50) | LMNAKMT2AKDM4EMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL6413522 | 0.74 | MAPT (0.47) | LMNAKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL6416975 | 0.72 | MAPT (0.51) | LMNAKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL6414665 | 0.72 | DDX3X (0.53) | LMNAKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL6414142 | 0.72 | MAPT (0.43) | LMNAKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL6416985 | 0.72 | MAPT (0.51) | LMNAKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL6414153 | 0.71 | STAT6 (0.38) | LMNAKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL6414619 | 0.71 | MEN1 (0.46) | LMNAKMT2AKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044270-A1 | OXADIAZOLOPYRAZINE DERIVATIVES AS PHARMACEUTICALLY ACTIVE COMPOUNDS | 4SC AG (DE) | 2005-05-19 | — | — | WO | disclosed |