Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | CA12 | O43570 | 3/20 | 0.71 |
| ▸ | CA1 | P00915 | 3/20 | 0.71 |
| ▸ | CA2 | P00918 | 3/20 | 0.71 |
| ▸ | CA6 | P23280 | 3/20 | 0.71 |
| ▸ | CA7 | P43166 | 3/20 | 0.71 |
| ▸ | CA9 | Q16790 | 3/20 | 0.71 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.71 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.71 |
| ▸ | CA5A | P35218 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | CA3 | P07451 | 2/20 | 0.71 |
| ▸ | MAOB | P27338 | 6/20 | 0.58 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.57 |
| ▸ | CA4 | P22748 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6418716 | 0.90 | SLC16A3 (0.71) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL6416335 | 0.89 | MAOB (0.57) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL6416333 | 0.89 | MAOB (0.57) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL26603107 | 0.88 | KDM4E (0.69) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL6415713 | 0.85 | MAOB (0.76) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL11337551 | 0.85 | ALDH1A1 (0.72) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL29963204 | 0.84 | KDM4E (1.00) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL978456 | 0.84 | KDM4E (1.00) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL6414543 | 0.83 | LMNA (0.62) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL17200990 | 0.80 | ALDH1A1 (0.51) | KDM4EALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005118584-A2 | SAFRAMYCIN ANALOGS AS THERAPEUTIC AGENTS IN THE TREATMENT OF CANCER | AXYS PHARMACEUTICALS, INC. (US) | 2005-12-15 | — | — | WO | disclosed |