Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22859825 | 0.80 | ALDH1A1 (0.44) | LMNAHTTALDH1A1ESR1ESR2 | |
| SCHEMBL14546327 | 0.80 | TAAR1 (0.34) | ESR1ESR2 | |
| SCHEMBL28807225 | 0.80 | ESR1 (0.37) | ESR1ESR2PTGS1PTGS2 | |
| SCHEMBL394775 | 0.79 | LMNA (0.41) | LMNAHTTALDH1A1ESR1ESR2 | |
| SCHEMBL8171810 | 0.78 | TSHR (0.46) | LMNAALDH1A1ESR1ESR2MAPT | |
| SCHEMBL14496740 | 0.78 | ALDH1A1 (0.37) | ALDH1A1ESR1ESR2NPC1MAPT | |
| SCHEMBL17399963 | 0.78 | ESR1 (0.68) | ALDH1A1ESR1ESR2MAPTCYP1A2 | |
| SCHEMBL14483928 | 0.78 | HPGD (0.38) | ALDH1A1ESR1ESR2NPC1MAPT | |
| SCHEMBL14484028 | 0.78 | ALDH1A1 (0.50) | ALDH1A1NPC1MAPTRAB9ACYP1A2 | |
| SCHEMBL8368071 | 0.78 | CYP3A4 (0.46) | ALDH1A1MAPTCYP3A4CCR2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113149971-A | 8- (indoletriazole) substituted coumarin compound and preparation method and application thereof | 港科鹏禾生物(苏州)有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-111196750-B | Preparation method of benzyl iodide and derivatives thereof | 清华大学 | 2020-11-10 | — | — | CN | disclosed |
| CN-111196750-A | Preparation method of benzyl iodide and derivatives thereof | 清华大学 | 2020-05-26 | — | — | CN | disclosed |
| US-9278959-B2 | Processes and reagents for making diaryliodonium salts | NUTECH VENTURES (US) | 2016-03-08 | — | — | US | disclosed |
| US-20140121371-A1 | PROCESSES AND REAGENTS FOR MAKING DIARYLIODONIUM SALTS | Ground Fluor Pharmaceuticals, Inc. (US) | 2014-05-01 | — | — | US | disclosed |
| EP-1770085-A1 | DIAMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME AND FUNGICIDE CONTAINING THE DERIVATIVE AS ACTIVE INGREDIENT | Mitsui Chemicals, Inc. (JP) | 2007-04-04 | — | — | EP | disclosed |
| EP-0958292-B1 | 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES | BASF AG (DE) | 2007-01-03 | — | — | EP | disclosed |
| US-20050006627-A1 | Sterically hindered phenol antioxidant granules having balanced hardness | ALBEMARLE CORPORATION | 2005-01-13 | — | — | US | disclosed |
| US-6800228-B1 | FORMING ABRASION RESISTANT, POLYMER DISPERSIBLE, DUSTLESS PELLETS; FORMING WET PASTE OF FRIABILITY REDUCING AGENT AND POWDER; DRYING WITHOUT MELTING | ALBEMARLE CORPORATION | 2004-10-05 | — | — | US | disclosed |
| EP-1268047-A2 | STERICALLY HINDERED PHENOL ANTIOXIDANT GRANULES HAVING BALANCED HARDNESS | ALBEMARLE CORPORATION (US) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001070869-A2 | STERICALLY HINDERED PHENOL ANTIOXIDANT GRANULES HAVING BALANCED HARDNESS | ALBEMARLE CORPORATION (US) | 2001-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140121371-A1 | PROCESSES AND REAGENTS FOR MAKING DIARYLIODONIUM SALTS | ABL1, ARSA, AADAC | LMNA 4445/4885HTT 3836/4885ALDH1A1 1821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.