SCHEMBL6416447

SCHEMBL6416447

C=CC(=O)N[C@H](O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
ALDH1A1 P00352 2/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP2C19 P33261 1/20 0.38
LMNA P02545 1/20 0.36
TGM2 P21980 1/20 0.35
THRB P10828 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL36707 1.00 TSHR (0.52) TSHRALDH1A1MAPK1TDP1CYP2C19
Water SCHEMBL851923 0.98 TSHR (0.50) TSHRALDH1A1MAPK1TDP1CYP2C19
Methoxymethane SCHEMBL363848 0.91 TSHR (0.50) TSHRALDH1A1MAPK1TDP1CYP2C19
Vinylsulfonic Acid SCHEMBL842294 0.88 TSHR (0.42) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL7109385 0.87
SCHEMBL9004293 0.84 TSHR (0.39) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL15263779 0.80 ZDHHC20 (0.45) TSHRALDH1A1MAPK1TDP1TGM2
SCHEMBL196271 0.77 TSHR (0.54) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL2437423 0.77 TSHR (0.54) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL3846200 0.76 TSHR (0.54) TSHRALDH1A1MAPK1TDP1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118223147-A Preparation method of antistatic graphene modified nylon special-shaped fiber 江苏江山红化纤有限责任公司 2024-06-21 CN disclosed
US-20050103629-A1 Isoelectric focusing gels and methods of use thereof Life Technologies Corporation 2005-05-19 US disclosed