SCHEMBL9004293

SCHEMBL9004293

C=CC(=O)NC(O)C(=O)O.C=CCOCC=C

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MAPT P10636 1/20 0.32
CACNA1B Q00975 1/20 0.32
APBA1 Q02410 1/20 0.32
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9283702 0.87 CA1 (0.35) TSHRCA1CA2CA7ALDH1A1
SCHEMBL6416447 0.84 TSHR (0.52) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL36707 0.84 TSHR (0.52) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL253107 0.84 MAPT (0.41) TSHRCA1CA2CA7ALDH1A1
SCHEMBL9000788 0.83 TSHR (0.41) TSHRCA1CA2CA7ALDH1A1
Water SCHEMBL851923 0.82 TSHR (0.50) TSHRALDH1A1MAPK1TDP1CYP2C19
Methoxymethane SCHEMBL363848 0.81 TSHR (0.50) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL1794180 0.78 MAPT (0.44) TSHRCA1CA2CA7ALDH1A1
Vinylsulfonic Acid SCHEMBL842294 0.74 TSHR (0.42) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL10987110 0.74 CASP1 (0.43) ALDH1A1MAPTCACNA1BAPBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4656308-A COATINGS AMERICAN CYANAMID COMPANY (US) 1987-04-07 US claimed
EP-3240835-B1 ELECTROSTATIC INK COMPOSITIONS HP INDIGO BV (NL) 2020-07-01 EP disclosed
EP-3240835-A1 ELECTROSTATIC INK COMPOSITIONS HP INDIGO B.V. (NL) 2017-11-08 EP disclosed
WO-2016173628-A1 ELECTROSTATIC INK COMPOSITIONS HEWLETT-PACKARD INDIGO B.V. (NL) 2016-11-03 WO disclosed
WO-2015165541-A1 ELECTROSTATIC INK COMPOSITIONS HEWLETT-PACKARD INDIGO B.V. (NL) 2015-11-05 WO disclosed
EP-2691480-A1 LIQUID TONER COMPOSITION Hewlett-Packard Indigo B.V. (NL) 2014-02-05 EP disclosed
WO-2012130303-A1 LIQUID TONER COMPOSITION HEWLETT-PACKARD INDIGO B.V. (NL) 2012-10-04 WO disclosed
EP-0733486-A3 Thermal dye transfer system with a dye-receiving element comprising an alkyl acrylamidoglycolate alkyl ether group EASTMAN KODAK COMPANY (US) 1996-11-06 EP disclosed
EP-0733486-A2 Thermal dye transfer system with a dye-receiving element comprising an alkyl acrylamidoglycolate alkyl ether group EASTMAN KODAK COMPANY (US) 1996-09-25 EP disclosed
US-5478688-A Liquid developer compositions with charge adjuvants of a copolymer of an alky acrylamidoglycolate alkyl ether and an alkenylester XEROX CORPORATION (US) 1995-12-26 US disclosed
US-5466551-A Image member including a grounding layer XEROX CORPORATION (US) 1995-11-14 US disclosed
US-5142019-A Oligomers formed from reaction of acrylamidoglycolate alkyl ethers with β-hydroxyalkylamines PPG INDUSTRIES, INC. (US) 1992-08-25 US disclosed
US-4778869-A COATINGS, ADHESIVES, MOLDINGS AMERICAN CYANAMID COMPANY (US) 1988-10-18 US disclosed
US-4656308-A COATINGS AMERICAN CYANAMID COMPANY (US) 1987-04-07 US disclosed
EP-0049910-B1 COPOLYMERS FORMED FROM ACTIVATED ESTER MONOMERS, AND COATING COMPOSITIONS CONTAINING SAID COPOLYMERS AMERICAN CYANAMID COMPANY (US) 1986-02-19 EP disclosed
US-4554337-A CROSSLINKING WITH ALKYL ACRYLAMIDOGLYCOLATE ALKYL ETHER RALSTON PURINA COMPANY (US) 1985-11-19 US disclosed
EP-0049910-A2 Copolymers formed from activated ester monomers, and coating compositions containing said copolymers AMERICAN CYANAMID COMPANY (US) 1982-04-21 EP disclosed
EP-0020000-A1 Activated ester monomers, polymers formed therefrom and coating compositions containing said polymers AMERICAN CYANAMID COMPANY (US) 1980-12-10 EP disclosed