SCHEMBL6416751

SCHEMBL6416751

CC(=O)c1ccc(Oc2ccc(OCc3ccccc3)c(C)c2)nc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.52
GRM2 Q14416 1/20 0.51
CYSLTR1 Q9Y271 1/20 0.51
FFAR4 Q5NUL3 2/20 0.48
FFAR1 O14842 1/20 0.47
OPRM1 P35372 4/20 0.47
OPRD1 P41143 3/20 0.47
OPRK1 P41145 3/20 0.47
RXRA P19793 1/20 0.46
RXRB P28702 1/20 0.46
RXRG P48443 1/20 0.46
ACACB O00763 3/20 0.45
ACACA Q13085 3/20 0.45
ALDH1A1 P00352 2/20 0.45
HTT P42858 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
MCL1 Q07820 1/20 0.45
BAK1 Q16611 1/20 0.45
MRGPRX4 Q96LA9 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6348828 0.92 GRM2 (0.54) GRM2CYSLTR1FFAR4FFAR1OPRM1
SCHEMBL6337233 0.91 MAOB (0.55) MAOBGRM2CYSLTR1FFAR1OPRM1
SCHEMBL6341725 0.89 OPRM1 (0.47) GRM2CYSLTR1FFAR4FFAR1OPRM1
SCHEMBL6338944 0.86 FFAR4 (0.43) GRM2CYSLTR1FFAR4FFAR1OPRM1
SCHEMBL6347635 0.85 MAOB (0.59) MAOBGRM2CYSLTR1OPRM1OPRD1
SCHEMBL6346472 0.85 MAOB (0.69) MAOBGRM2CYSLTR1OPRM1OPRD1
SCHEMBL6338798 0.84 FFAR4 (0.54) FFAR4FFAR1RXRARXRBRXRG
SCHEMBL6337213 0.83 NR4A2 (0.52) MAOBGRM2CYSLTR1FFAR1RXRA
SCHEMBL6341086 0.81 MEN1 (0.47) MAOBFFAR1OPRM1OPRD1OPRK1
SCHEMBL385027 0.80 FFAR4 (0.62) MAOBFFAR4RXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6890932-B2 Immunoglobulin e antibody suppressors TEIJIN LIMITED (JP) 2005-05-10 US disclosed
EP-1101755-B1 ANTHRANILIC ACID DERIVATIVES TEIJIN LTD (JP) 2004-10-06 EP disclosed
US-20030232811-A1 Immunoglobulin e antibody suppressors TEIJIN LIMITED 2003-12-18 US disclosed
US-6649656-B1 Anticarcinogenic, antiallergen, antishock, and antiasthmatic agents TEIJIN LIMITED (JP) 2003-11-18 US disclosed
EP-1101755-A1 ANTHRANILIC ACID DERIVATIVES TEIJIN LIMITED (JP) 2001-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030232811-A1 Immunoglobulin e antibody suppressors IGLV6-57, FCGRT, IGSF11 MAOB 2681/4885GRM2 3341/4885CYSLTR1 940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.