SCHEMBL6338798

SCHEMBL6338798

Cc1cc(Oc2ccc(CC(=O)O)cn2)ccc1OCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 5/20 0.54
FFAR1 O14842 6/20 0.52
PPARD Q03181 2/20 0.47
PPARG P37231 1/20 0.47
ACACB O00763 3/20 0.45
ACACA Q13085 3/20 0.45
MCL1 Q07820 1/20 0.45
BAK1 Q16611 1/20 0.45
RXRA P19793 2/20 0.45
RXRB P28702 2/20 0.45
RXRG P48443 2/20 0.45
SLC22A12 Q96S37 1/20 0.43
LIPE Q05469 1/20 0.43
MRGPRX4 Q96LA9 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6349045 0.91 PPARD (0.49) FFAR4FFAR1PPARDPPARGACACB
SCHEMBL6348828 0.85 GRM2 (0.54) FFAR4FFAR1MCL1BAK1RXRA
SCHEMBL6416751 0.84 MAOB (0.52) FFAR4FFAR1PPARDPPARGACACB
SCHEMBL6346488 0.84 CTSV (0.46) FFAR4FFAR1ACACBACACAMCL1
SCHEMBL6341556 0.84 ALOX5 (0.51) FFAR4FFAR1PPARGACACBACACA
SCHEMBL6338656 0.83 ACACB (0.55) FFAR4FFAR1ACACBACACA
SCHEMBL6338589 0.83 ALDH1A1 (0.44) FFAR4FFAR1
SCHEMBL6341725 0.83 OPRM1 (0.47) FFAR4FFAR1ACACBACACARXRA
SCHEMBL2793815 0.80 FFAR4 (0.74) FFAR4FFAR1RXRARXRBRXRG
SCHEMBL6337468 0.80 MEN1 (0.46) FFAR4FFAR1LIPE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6890932-B2 Immunoglobulin e antibody suppressors TEIJIN LIMITED (JP) 2005-05-10 US disclosed
EP-1101755-B1 ANTHRANILIC ACID DERIVATIVES TEIJIN LTD (JP) 2004-10-06 EP disclosed
US-20030232811-A1 Immunoglobulin e antibody suppressors TEIJIN LIMITED 2003-12-18 US disclosed
US-6649656-B1 Anticarcinogenic, antiallergen, antishock, and antiasthmatic agents TEIJIN LIMITED (JP) 2003-11-18 US disclosed
EP-1101755-A1 ANTHRANILIC ACID DERIVATIVES TEIJIN LIMITED (JP) 2001-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030232811-A1 Immunoglobulin e antibody suppressors IGLV6-57, FCGRT, IGSF11 FFAR4 2194/4885FFAR1 1564/4885PPARD 1257/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.