Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6418208 | 0.87 | ALDH1A1 (0.60) | MAPTALDH1A1LMNAHPGDTSHR | |
| SCHEMBL6414178 | 0.87 | ALDH1A1 (0.54) | MAPTALDH1A1LMNAHTR6TP53 | |
| SCHEMBL19710644 | 0.75 | ALDH1A1 (0.72) | MAPTALDH1A1RAB9ALMNAHPGD | |
| SCHEMBL12172775 | 0.72 | ALDH1A1 (0.74) | MAPTALDH1A1RAB9ALMNATSHR | |
| SCHEMBL8230032 | 0.72 | ALDH1A1 (0.61) | MAPTALDH1A1RAB9ALMNAHPGD | |
| SCHEMBL630715 | 0.72 | ALDH1A1 (0.66) | MAPTALDH1A1RAB9ALMNAHPGD | |
| SCHEMBL10501035 | 0.70 | ALDH1A1 (0.60) | MAPTALDH1A1RAB9ALMNAHPGD | |
| SCHEMBL6415443 | 0.70 | TSHR (0.59) | MAPTALDH1A1RAB9ALMNATSHR | |
| SCHEMBL4464556 | 0.70 | CNR1 (0.65) | MAPTALDH1A1RAB9ALMNATSHR | |
| SCHEMBL14758455 | 0.69 | TSHR (0.78) | MAPTALDH1A1RAB9ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050130989-A1 | N-arylheteroaromatic products compositions containing them and use thereof | AVENTIS PHARMA S. A. (FR) | 2005-06-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050130989-A1 | N-arylheteroaromatic products compositions containing them and use thereof | AHR, NQO1, ARNT | MAPT 4098/4885ALDH1A1 360/4885RAB9A 2030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.