Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Phosphonate SCHEMBL7116871 | 0.84 | CA2 (0.73) | CA2GABRR1GABBR2GABBR1LMNA | |
| Methyl Phosphonate SCHEMBL641731 | 0.84 | CA2 (0.73) | CA2GABRR1GABBR2GABBR1LMNA | |
| Phosphoric Acid SCHEMBL1702344 | 0.84 | CA2 (0.36) | CA2 | |
| Methyl Phosphonate SCHEMBL1500472 | 0.84 | CA2 (0.73) | CA2GABRR1GABBR2GABBR1LMNA | |
| SCHEMBL77699 | 0.79 | — | — | |
| SCHEMBL4447889 | 0.79 | — | — | |
| Ethane SCHEMBL4370310 | 0.79 | — | — | |
| SCHEMBL25523 | 0.78 | — | — | |
| Methyl Phosphonate SCHEMBL29461628 | 0.78 | CA2 (1.00) | CA2GABRR1GABBR2GABBR1LMNA | |
| Methyl Phosphonate SCHEMBL21791 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119410-B2 | Apoptosis modulator Bcl-B and methods for making and using same | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2012-02-21 | — | — | US | disclosed |
| US-20110190168-A1 | APOPTOSIS MODULATOR BCL-B AND METHODS FOR MAKING AND USING SAME | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-08-04 | — | — | US | disclosed |