Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.47 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.47 |
| ▸ | POLG | P54098 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 7/20 | 0.41 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.38 |
| ▸ | DTYMK | P23919 | 2/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | KRAS | P01116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6421906 | 0.91 | POLB (0.59) | POLBP2RY2P2RY4P2RY6POLG | |
| SCHEMBL8185378 | 0.91 | POLB (0.59) | POLBP2RY2P2RY4P2RY6POLG | |
| SCHEMBL29875948 | 0.86 | POLB (0.56) | POLBP2RY2P2RY4P2RY6POLG | |
| SCHEMBL29875815 | 0.80 | POLB (0.51) | POLBP2RY2P2RY4P2RY6PNP | |
| SCHEMBL4624825 | 0.80 | PNP (0.47) | POLBPNP | |
| SCHEMBL367683 | 0.80 | PNP (0.47) | POLBPNP | |
| SCHEMBL29875802 | 0.79 | POLB (0.46) | POLBP2RY2P2RY4P2RY6PNP | |
| SCHEMBL20324650 | 0.77 | POLB (0.47) | POLBP2RY2P2RY4P2RY6PNP | |
| Deoxyguanosine Triphosphate SCHEMBL2820367 | 0.76 | POLB (0.81) | POLBP2RY2P2RY4P2RY6POLG | |
| Deoxyguanosine Triphosphate SCHEMBL80609 | 0.76 | POLB (0.81) | POLBP2RY2P2RY4P2RY6POLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1589028-A2 | Modified oligonucleotides, their preparation and their use | Aventis Pharma Deutschland GmbH (DE) | 2005-10-26 | — | — | EP | disclosed |
| EP-0680969-B1 | Modified oligonucleotides, their preparation and their use | AVENTIS PHARMA GMBH (DE) | 2005-07-27 | — | — | EP | disclosed |
| EP-0680969-A2 | Modified oligonucleotides, their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-11-08 | — | — | EP | disclosed |