Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.59 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.55 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.55 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.55 |
| ▸ | POLG | P54098 | 1/20 | 0.46 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.45 |
| ▸ | DTYMK | P23919 | 2/20 | 0.44 |
| ▸ | PNP | P00491 | 2/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | KRAS | P01116 | 2/20 | 0.44 |
| ▸ | TYMS | P04818 | 1/20 | 0.42 |
| ▸ | POLA1 | P09884 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6421906 | 1.00 | POLB (0.59) | POLBP2RY2P2RY4P2RY6POLG | |
| SCHEMBL29875948 | 0.94 | POLB (0.56) | POLBP2RY2P2RY4P2RY6POLG | |
| SCHEMBL6417484 | 0.91 | POLB (0.53) | POLBP2RY2P2RY4P2RY6POLG | |
| SCHEMBL29875815 | 0.84 | POLB (0.51) | POLBP2RY2P2RY4P2RY6PNP | |
| SCHEMBL3042901 | 0.84 | POLB (0.81) | POLBP2RY2P2RY4P2RY6POLG | |
| SCHEMBL16699229 | 0.84 | POLB (0.81) | POLBP2RY2P2RY4P2RY6POLG | |
| Deoxyguanosine Triphosphate SCHEMBL18785123 | 0.84 | POLB (0.81) | POLBP2RY2P2RY4P2RY6POLG | |
| Deoxyguanosine Triphosphate SCHEMBL12729493 | 0.84 | POLB (0.81) | POLBP2RY2P2RY4P2RY6POLG | |
| SCHEMBL5314160 | 0.84 | POLB (0.59) | POLBP2RY2P2RY4P2RY6POLG | |
| SCHEMBL8091449 | 0.84 | POLB (0.59) | POLBP2RY2P2RY4P2RY6POLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6066720-A | WITH AT LEAST ONE 8-AZAPURINE BASE; FORMS MORE STABLE HYBRIDIZATION COMPLEXES WITH NUCLEIC ACIDS; FOR ANTISENSE AGENTS, DIAGNOSTIC AGENTS, PROBES, PRIMERS | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-23 | — | — | US | disclosed |
| US-5789562-A | STABLE HYBRIDIZATION COMPLEXES WITH NUCLEI ACIDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |