Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.39 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 7/20 | 0.38 |
| ▸ | TOP2A | P11388 | 2/20 | 0.36 |
| ▸ | ATG7 | O95352 | 3/20 | 0.35 |
| ▸ | POLA1 | P09884 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | HINT1 | P49773 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367683 | 0.84 | PNP (0.47) | POLBPNPPOLA1 | |
| SCHEMBL4624825 | 0.84 | PNP (0.47) | POLBPNPPOLA1 | |
| SCHEMBL14208959 | 0.83 | POLB (0.65) | POLBP2RY2P2RY4P2RY6PNP | |
| SCHEMBL29461569 | 0.83 | POLB (0.65) | POLBP2RY2P2RY4P2RY6PNP | |
| SCHEMBL24370786 | 0.83 | POLB (0.65) | POLBP2RY2P2RY4P2RY6PNP | |
| SCHEMBL8185378 | 0.80 | POLB (0.59) | POLBP2RY2P2RY4P2RY6PNP | |
| SCHEMBL6421906 | 0.80 | POLB (0.59) | POLBP2RY2P2RY4P2RY6PNP | |
| SCHEMBL6417484 | 0.79 | POLB (0.53) | POLBP2RY2P2RY4P2RY6PNP | |
| SCHEMBL29875815 | 0.79 | POLB (0.51) | POLBP2RY2P2RY4P2RY6PNP | |
| SCHEMBL20621581 | 0.78 | POLB (0.45) | POLBP2RY2P2RY4P2RY6TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240150389-A1 | MODIFIED GUANINES | NUCLERA LTD (GB) | 2024-05-09 | — | — | US | disclosed |
| WO-2022175685-A1 | MODIFIED GUANINES | NUCLERA NUCLEICS LTD (GB) | 2022-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240150389-A1 | MODIFIED GUANINES | NSUN2, RNMT, RNGTT | POLB 29/4885P2RY2 1972/4885P2RY4 1857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.