Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11442842 | 0.89 | NAAA (0.43) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL5181522 | 0.85 | MGAM (0.43) | ALDH1A1HSD17B10TDP1 | |
| SCHEMBL2237455 | 0.76 | — | — | |
| SCHEMBL15020942 | 0.76 | GSTP1 (0.31) | — | |
| SCHEMBL10527666 | 0.74 | ALDH1A1 (0.38) | ALDH1A1LMNAESR1TSHR | |
| SCHEMBL7197439 | 0.73 | ALDH1A1 (0.50) | ALDH1A1LMNAKDM4EHPGDESR1 | |
| SCHEMBL5137766 | 0.73 | CYP3A4 (0.41) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL29159725 | 0.73 | KMT2A (0.36) | ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL27456435 | 0.72 | ALDH1A1 (0.38) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL472103 | 0.71 | ALDH1A1 (0.47) | ALDH1A1LMNAKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050163827-A1 | Transdermal therapeutic delivery system | ZECH HERBERT (AT) | 2005-07-28 | — | — | US | claimed |
| CN-115209890-A | Alkannin and arylnaphthalene lignan for inhibiting expression of proinflammatory genes and pharmaceutical composition containing same | 宝洁公司 | 2022-10-18 | — | — | CN | disclosed |
| US-20050163827-A1 | Transdermal therapeutic delivery system | ZECH HERBERT (AT) | 2005-07-28 | — | — | US | disclosed |