Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | GUSB | P08236 | 3/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3370745 | 1.00 | MAOA (0.38) | MAOAMAOBATMABCB1GUSB | |
| SCHEMBL3370754 | 1.00 | MAOA (0.38) | MAOAMAOBATMABCB1GUSB | |
| SCHEMBL3370749 | 1.00 | MAOA (0.38) | MAOAMAOBATMABCB1GUSB | |
| SCHEMBL23894634 | 0.77 | MAOA (0.35) | MAOAMAOBATMABCB1 | |
| SCHEMBL3260378 | 0.77 | MAOA (0.35) | MAOAMAOBATM | |
| SCHEMBL25056919 | 0.77 | ABCB1 (0.44) | MAOAMAOBATMABCB1GUSB | |
| SCHEMBL312107 | 0.76 | ABCG2 (0.36) | MAOAMAOB | |
| SCHEMBL19885491 | 0.75 | MAOA (0.58) | MAOAMAOBATMHDAC3HDAC4 | |
| SCHEMBL11409097 | 0.74 | ABCB1 (0.35) | MAOAMAOBABCB1 | |
| SCHEMBL13551756 | 0.73 | ABCB1 (0.41) | MAOAMAOBABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499618-A1 | FURYL COMPOUNDS | AstraZeneca AB (SE) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003087102-A1 | FURYL COMPOUNDS | ASTRAZENECA AB (SE) | 2003-10-23 | — | — | WO | disclosed |