SCHEMBL3370749

SCHEMBL3370749

BrC1Oc2ccccc2C1Br

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
ATM Q13315 1/20 0.32
ABCB1 P08183 2/20 0.32
GUSB P08236 3/20 0.31
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC10 Q969S8 1/20 0.31
HDAC11 Q96DB2 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
HDAC9 Q9UKV0 1/20 0.31
HDAC5 Q9UQL6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6417599 1.00 MAOA (0.38) MAOAMAOBATMABCB1GUSB
SCHEMBL3370745 1.00 MAOA (0.38) MAOAMAOBATMABCB1GUSB
SCHEMBL3370754 1.00 MAOA (0.38) MAOAMAOBATMABCB1GUSB
SCHEMBL23894634 0.77 MAOA (0.35) MAOAMAOBATMABCB1
SCHEMBL3260378 0.77 MAOA (0.35) MAOAMAOBATM
SCHEMBL25056919 0.77 ABCB1 (0.44) MAOAMAOBATMABCB1GUSB
SCHEMBL312107 0.76 ABCG2 (0.36) MAOAMAOB
SCHEMBL19885491 0.75 MAOA (0.58) MAOAMAOBATMHDAC3HDAC4
SCHEMBL11409097 0.74 ABCB1 (0.35) MAOAMAOBABCB1
SCHEMBL13551756 0.73 ABCB1 (0.41) MAOAMAOBABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12063852-B2 Organic electroluminescence device and monoamine compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2024-08-13 US disclosed
CN-111718357-B Organic electroluminescent device and monoamine compound for organic electroluminescent device 三星显示有限公司 2024-07-16 CN disclosed
EP-3889236-B1 ORGANIC LIGHT-EMITTING ELEMENT USING POLYCYCLIC AROMATIC DERIVATIVE COMPOUND SFC CO LTD (KR) 2023-11-22 EP disclosed
EP-3754737-B1 ORGANIC COMPOUND FOR ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DIODE INCLUDING SAME SFC CO LTD (KR) 2023-08-16 EP disclosed
US-20230232650-A1 ORGANOELECTROLUMINESCENT DEVICE USING POLYCYCLIC AROMATIC COMPOUNDS SFC CO., LTD (KR) 2023-07-20 US disclosed
US-20230232650-A1 ORGANOELECTROLUMINESCENT DEVICE USING POLYCYCLIC AROMATIC COMPOUNDS SFC CO., LTD (KR) 2023-07-20 US disclosed
US-20230209999-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MONOAMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230183200-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SFC CO., LTD (KR) 2023-06-15 US disclosed
US-20230183200-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SFC CO., LTD (KR) 2023-06-15 US disclosed
US-20230165032-A1 ORGANOELECTROLUMINESCENT DEVICE USING POLYCYCLIC AROMATIC DERIVATIVE COMPOUNDS SFC CO., LTD (KR) 2023-05-25 US disclosed
US-5807889-A PSYCHOLOGICAL AND NERVOUS SYSTEM DISORDERS H. LUNDBECK A/S (DK) 1998-09-15 US disclosed
EP-0673360-B1 AMINOMETHYLINDANS, -BENZOFURANES AND -BENZOTHIOPHENES LUNDBECK & CO AS H (DK) 1998-08-26 EP disclosed
EP-0619297-B1 Fungicides for the control of take-all desease of plants MONSANTO CO (US) 1997-06-18 EP disclosed
EP-0673360-A1 AMINOMETHYLINDANS, -BENZOFURANES AND -BENZOTHIOPHENES H. LUNDBECK A/S (DK) 1995-09-27 EP disclosed
EP-0619297-A1 Fungicides for the control of take-all desease of plants MONSANTO COMPANY (US) 1994-10-12 EP disclosed
WO-1994013620-A1 AMINOMETHYLINDANS, -BENZOFURANES AND -BENZOTHIOPHENES H. LUNDBECK A/S (DK) 1994-06-23 WO disclosed
EP-0207605-B1 HYPOGLYCEMIC THIAZOLIDINEDIONES PFIZER INC. (US) 1990-02-07 EP disclosed
US-4703052-A Hypoglycemic thiazolidinediones PFIZER INC. (US) 1987-10-27 US disclosed
EP-0207605-A1 Hypoglycemic thiazolidinediones PFIZER INC. (US) 1987-01-07 EP disclosed
WO-1986007056-A1 HYPOGLYCEMIC THIAZOLIDINEDIONES PFIZER INC. (US) 1986-12-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12063852-B2 Organic electroluminescence device and monoamine compound for organic electroluminescence device COMT, MAOA, MAOB MAOA 2/4885MAOB 3/4885ATM 2898/4885
US-20230183200-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME TRPA1, CRY2, SUN2 MAOA 768/4885MAOB 1528/4885ATM 1605/4885
US-20230209999-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MONOAMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE COMT, MAOA, MAOB MAOA 2/4885MAOB 3/4885ATM 2898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.