Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | PPM1B | O75688 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11442843 | 0.89 | ATM (0.46) | HCAR2NAAADGKAALDH1A1ATM | |
| SCHEMBL27459005 | 0.87 | NAAA (0.52) | HCAR2NAAADGKAALDH1A1LMNA | |
| SCHEMBL6417833 | 0.84 | GAA (0.44) | HCAR2ALDH1A1LMNAHSD17B10NPSR1 | |
| SCHEMBL28139810 | 0.78 | HCAR2 (0.38) | HCAR2NAAADGKAALDH1A1LMNA | |
| SCHEMBL9473404 | 0.77 | — | — | |
| SCHEMBL6420493 | 0.75 | — | — | |
| SCHEMBL8029426 | 0.74 | HCAR2 (0.45) | HCAR2NAAADGKAALDH1A1LMNA | |
| SCHEMBL10580042 | 0.74 | DGKA (0.42) | HCAR2NAAADGKAALDH1A1LMNA | |
| SCHEMBL8196636 | 0.74 | DGKA (0.42) | HCAR2NAAADGKAALDH1A1LMNA | |
| SCHEMBL9579787 | 0.74 | DGKA (0.42) | HCAR2NAAADGKAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050163827-A1 | Transdermal therapeutic delivery system | ZECH HERBERT (AT) | 2005-07-28 | — | — | US | claimed |
| CN-115209890-A | Alkannin and arylnaphthalene lignan for inhibiting expression of proinflammatory genes and pharmaceutical composition containing same | 宝洁公司 | 2022-10-18 | — | — | CN | disclosed |
| US-20050163827-A1 | Transdermal therapeutic delivery system | ZECH HERBERT (AT) | 2005-07-28 | — | — | US | disclosed |