SCHEMBL641784

SCHEMBL641784

C=C(C)C(=O)OCCOC(=O)C(=C)C.C=Cc1ccccc1C=C

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.49
TSHR P16473 4/20 0.43
POLB P06746 2/20 0.43
APEX1 P27695 1/20 0.43
HTT P42858 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
ELANE P08246 1/20 0.38
CYP3A4 P08684 1/20 0.36
ALDH1A1 P00352 4/20 0.36
MAPT P10636 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
PLIN1 O60240 1/20 0.36
LMNA P02545 1/20 0.36
PLIN5 Q00G26 1/20 0.36
ABHD5 Q8WTS1 1/20 0.36
RAD52 P43351 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7538516 0.92 THRB (0.41) THRBTSHRPOLBAPEX1HTT
SCHEMBL28191642 0.92 TSHR (0.47) THRBTSHRPOLBAPEX1HTT
SCHEMBL4421001 0.90 TSHR (0.39) THRBTSHRPOLBAPEX1HTT
SCHEMBL28069492 0.89 TSHR (0.45) THRBTSHRPOLBAPEX1HTT
SCHEMBL1614699 0.89 TSHR (0.57) THRBTSHRPOLBAPEX1HTT
SCHEMBL28921993 0.88 MAPT (0.49) THRBTSHRPOLBTDP1ALDH1A1
SCHEMBL28630380 0.88 TSHR (0.64) THRBTSHRPOLBAPEX1HTT
SCHEMBL672829 0.87 CYP3A4 (0.49) TSHRPOLBCA1CA2ELANE
SCHEMBL27886581 0.87 TSHR (0.67) THRBTSHRPOLBAPEX1HTT
SCHEMBL29152805 0.87 TSHR (0.67) THRBTSHRPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107102054-B It is a kind of for detecting the preparation method of ginsenoside Re's molecular engram sensor 济南大学 2018-12-21 CN claimed
EP-0920440-B1 DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS CORNELL RES FOUNDATION INC (US) 2012-08-22 EP claimed
EP-0856032-A4 ACRYLIC COMPOSITIONS ICI ACRYLICS INC (US) 1999-09-22 EP claimed
EP-0856032-A1 ACRYLIC COMPOSITIONS ICI Acrylics, Inc. (US) 1998-08-05 EP claimed
US-5674962-A CONSISTING OF STYRENE COMPONENT, BUTYL ACRYLATE AND/OR (METH)ACRYLATE AND A DIVINYL COMPOUND AS MONOMERS AND HAVING PREFERRED PHYSICAL PROPERTIES, FOR HIGH SPEED ELECTROGRAPHIC PRINTING MITSUBISHI RAYON COMPANY LTD. (JP) 1997-10-07 US claimed
WO-1997014749-A1 ACRYLIC COMPOSITIONS ICI ACRYLICS INC. (US) 1997-04-24 WO claimed
US-4093570-A CROSSLINKABLE, MIXED ORGANIC MEDIUM; ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1978-06-06 US claimed
EP-3233230-B1 TARGET MOLECULE CAPTURE FROM CRUDE SOLUTIONS MERCK PATENT GMBH (DE) 2024-06-12 EP disclosed
WO-2020149206-A1 METHOD FOR PRODUCING ACRYLIC RESIN FILM コニカミノルタ株式会社 2020-07-23 WO disclosed
US-10617975-B2 Target molecule capture from crude solutions MERCK PATENT GMBH (DE) 2020-04-14 US disclosed
EP-3163334-B1 OPTICAL RESIN COMPOSITION AND FILM KANEKA CORP (JP) 2020-04-01 EP disclosed
US-10597525-B2 Resin composition and film thereof KANEKA CORPORATION (JP) 2020-03-24 US disclosed
US-10598822-B2 Optical resin material and optical film KANEKA CORPORATION (JP) 2020-03-24 US disclosed
EP-0856032-A4 ACRYLIC COMPOSITIONS ICI ACRYLICS INC (US) 1999-09-22 EP disclosed
EP-0856032-A1 ACRYLIC COMPOSITIONS ICI Acrylics, Inc. (US) 1998-08-05 EP disclosed
EP-0802928-A1 USE OF POLYGLYCEROL ALIPHATIC ETHER EMULSIFIERS IN MAKING HIGH INTERNAL PHASE EMULSIONS THAT CAN BE POLYMERIZED TO PROVIDE ABSORBENT FOAMS THE PROCTER & GAMBLE COMPANY (US) 1997-10-29 EP disclosed
WO-1997014749-A1 ACRYLIC COMPOSITIONS ICI ACRYLICS INC. (US) 1997-04-24 WO disclosed
WO-1996021679-A1 USE OF POLYGLYCEROL ALIPHATIC ETHER EMULSIFIERS IN MAKING HIGH INTERNAL PHASE EMULSIONS THAT CAN BE POLYMERIZED TO PROVIDE ABSORBENT FOAMS THE PROCTER & GAMBLE COMPANY (US) 1996-07-18 WO disclosed
US-4472554-A POLYMERIC ACIDIFICATION AGENT MOBAY CHEMICAL CORPORATION (US) 1984-09-18 US disclosed
US-4228205-A HYDROPHILIC FILLER CESKOSLOVENSKA AKADEMIE VED (CS) 1980-10-14 US disclosed