SCHEMBL672829

SCHEMBL672829

C=CCOC(=O)C(=C)C.C=Cc1ccccc1C=C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.49
ALDH1A1 P00352 5/20 0.45
MEN1 O00255 5/20 0.45
KMT2A Q03164 5/20 0.45
MAPT P10636 5/20 0.45
MAPK1 P28482 4/20 0.45
KDM4E B2RXH2 3/20 0.43
GLA P06280 1/20 0.43
HSD17B10 Q99714 3/20 0.43
TSHR P16473 3/20 0.43
NPSR1 Q6W5P4 1/20 0.40
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
PKM P14618 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
RHOA P61586 1/20 0.38
POLB P06746 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10751696 0.91 CYP3A4 (0.44) CYP3A4ALDH1A1MEN1KMT2AMAPT
SCHEMBL17685584 0.90 ALDH1A1 (0.42) CYP3A4ALDH1A1MEN1KMT2AMAPT
SCHEMBL4421001 0.87 TSHR (0.39) CYP3A4ALDH1A1MEN1KMT2AMAPT
SCHEMBL641784 0.87 THRB (0.49) CYP3A4ALDH1A1MEN1KMT2AMAPT
Styrene SCHEMBL88055 0.86 MEN1 (0.50) CYP3A4ALDH1A1MEN1KMT2AMAPT
SCHEMBL28921993 0.85 MAPT (0.49) ALDH1A1MEN1KMT2AMAPTKDM4E
Phenol SCHEMBL10749165 0.84 CYP3A4 (0.49) CYP3A4ALDH1A1MEN1KMT2AMAPT
SCHEMBL28067222 0.83 CYP3A4 (0.43) CYP3A4ALDH1A1MEN1KMT2AMAPT
Styrene SCHEMBL4287862 0.83 MEN1 (0.48) CYP3A4ALDH1A1MEN1KMT2AMAPT
SCHEMBL27353705 0.83 CYP3A4 (0.47) CYP3A4ALDH1A1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4349477-A1 HYBRID GRAFTED AND HYPERBRANCHED ANION EXCHANGERS Dionex Corporation (US) 2024-04-10 EP disclosed
US-20240110026-A1 HYBRID GRAFTED AND HYPERBRANCHED ANION EXCHANGERS DIONEX CORPORATION 2024-04-04 US disclosed
CN-117718084-A Grafted and hyperbranched mixed anion exchangers 戴安公司 2024-03-19 CN disclosed
EP-3520804-A1 COMPOSITION FOR CARTILAGE The Regents of The University of California (US) 2019-08-07 EP disclosed
EP-2435468-B1 FIBROMODULIN PEPTIDE UNIV CALIFORNIA (US) 2018-11-14 EP disclosed
CN-105722868-A Method for producing thermally expandable microspheres and use thereof 松本油脂制药株式会社 2016-06-29 CN disclosed
EP-2606121-B1 COMPOSITIONS COMRPISING PERIVASCULAR STEM CELLS AND NELL-1 PROTEIN UNIV CALIFORNIA (US) 2016-05-11 EP disclosed
US-9301976-B2 Compositions comprising perivascular stem cells and nell-1 protein THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-04-05 US disclosed
US-20130309207-A1 COMPOSITIONS COMPRISING PERIVASCULAR STEM CELLS AND NELL-1 PROTEIN THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-11-21 US disclosed
EP-2606121-A2 COMPOSITIONS COMRPISING PERIVASCULAR STEM CELLS AND NELL-1 PROTEIN The Regents of the University of California (US) 2013-06-26 EP disclosed
EP-2435468-A2 FIBROMODULIN PEPTIDE The Regents of the University of California (US) 2012-04-04 EP disclosed
WO-2012024573-A2 COMPOSITIONS COMRPISING PERIVASCULAR STEM CELLS AND NELL-1 PROTEIN THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-02-23 WO disclosed
WO-2011022071-A2 CARDIAC COMPOSITIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-02-24 WO disclosed
WO-2011022070-A2 PERIVASCULAR STEM CELL COMPOSITION FOR BONE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-02-24 WO disclosed
WO-2010138637-A2 FIBROMODULIN PEPTIDE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-12-02 WO disclosed
US-7687462-B2 Composition for promoting cartilage formation or repair comprising a nell gene product and method of treating cartilage-related conditions using such composition THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-03-30 US disclosed
EP-2089048-A2 COMPOSITION FOR CARTILAGE The Regents of the University of California (US) 2009-08-19 EP disclosed
WO-2008073631-A9 COMPOSITION FOR CARTILAGE UNIV CALIFORNIA (US) 2008-09-18 WO disclosed
WO-2008073631-A2 COMPOSITION FOR CARTILAGE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-06-19 WO disclosed
US-20070134291-A1 Composition for cartilage NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-06-14 US disclosed