SCHEMBL6417995

SCHEMBL6417995

CC(C)(CO)NC(=O)c1ccc(F)cn1

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 17/20 0.61
CNR1 P21554 12/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6419679 0.84 ANO1 (0.47) CNR2CNR1
SCHEMBL29503927 0.84 ANO1 (0.47) CNR2CNR1
SCHEMBL6415912 0.83 CNR2 (0.62) CNR2CNR1
SCHEMBL17841457 0.82 CNR2 (0.51) CNR2CNR1
SCHEMBL14838763 0.78 CYP1A2 (0.61)
SCHEMBL29836034 0.78 CNR2 (0.49) CNR2CNR1
SCHEMBL18130923 0.77 CNR2 (0.52) CNR2CNR1
SCHEMBL3757683 0.76 NPC1 (0.52) CNR2CNR1
SCHEMBL428478 0.75 NPC1 (0.49) CNR1
SCHEMBL108305 0.75 P2RX7 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6936736-B2 Amide derivative SUMITOMO MANUFACTURING COMPANY LIMITED (JP) 2005-08-30 US disclosed
EP-1034783-B1 AMIDE DERIVATIVES FOR THE TREATMENT OF RETINAL NEURODEGENERATIVE DISORDERS SUMITOMO PHARMA (JP) 2004-12-15 EP disclosed
US-20020147204-A1 Amide derivative SUMITOMO PHARMACEUTICALS COMPANY, LIMITED 2002-10-10 US disclosed
US-6384033-B1 DRUGS FOR VISION DEFECTS SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2002-05-07 US disclosed
CN-1278167-A Amide derivatives SUMITOMO PHARMA (JP) 2000-12-27 CN disclosed
EP-1034783-A1 AMIDE DERIVATIVES SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2000-09-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020147204-A1 Amide derivative ALDH1A2, NR1H2, HDAC3 CNR2 183/4885CNR1 206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.