Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 7/20 | 0.40 |
| ▸ | LDHB | P07195 | 6/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 5/20 | 0.38 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6418358 | 1.00 | LDHA (0.40) | LDHALDHBACMSDHAO1BIRC5 | |
| SCHEMBL6416293 | 0.92 | ALDH1A1 (0.41) | BIRC5KMT2AMCL1NPC1RAB9A | |
| SCHEMBL6435669 | 0.81 | MAPT (0.44) | KMT2AMCL1NPC1RAB9AMEN1 | |
| SCHEMBL6435995 | 0.79 | BIRC5 (0.50) | BIRC5KMT2AMCL1NPC1RAB9A | |
| SCHEMBL6432253 | 0.79 | RPA1 (0.44) | KMT2AMCL1NPC1RAB9AMEN1 | |
| SCHEMBL6418352 | 0.79 | BIRC5 (0.60) | LDHALDHBHAO1BIRC5AKT1 | |
| SCHEMBL6433045 | 0.79 | KDM4E (0.45) | KMT2AMCL1NPC1RAB9AMEN1 | |
| SCHEMBL6422204 | 0.77 | KDM4E (0.44) | KMT2AMCL1NPC1RAB9AMEN1 | |
| SCHEMBL6415140 | 0.76 | MAPT (0.42) | KMT2AMCL1RAB9AMEN1KDM4E | |
| SCHEMBL6414398 | 0.76 | ALDH1A1 (0.43) | LDHALDHBKMT2AMCL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143382-A1 | Heterocyclic compounds as pharmaceutically active compounds | 4SC AG (DE) | 2005-06-30 | — | — | US | disclosed |
| WO-2005044270-A1 | OXADIAZOLOPYRAZINE DERIVATIVES AS PHARMACEUTICALLY ACTIVE COMPOUNDS | 4SC AG (DE) | 2005-05-19 | — | — | WO | disclosed |
| EP-1529531-A1 | Oxadiazolopyrazine derivatives as pharmaceutically active compounds | 4SC AG (DE) | 2005-05-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143382-A1 | Heterocyclic compounds as pharmaceutically active compounds | NR5A2, NR1H2, NR2C2 | LDHA 3775/4885LDHB 4014/4885ACMSD 3592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.