SCHEMBL641853

SCHEMBL641853

Nc1ccc(C(=O)Nc2ccccc2)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.81
MEN1 O00255 3/20 0.81
KMT2A Q03164 3/20 0.81
LMNA P02545 1/20 0.81
PKM P14618 1/20 0.81
APEX1 P27695 1/20 0.81
TDP1 Q9NUW8 1/20 0.81
PTPN1 P18031 3/20 0.71
HDAC2 Q92769 2/20 0.69
HDAC8 Q9BY41 1/20 0.69
HDAC6 Q9UBN7 1/20 0.69
HDAC3 O15379 1/20 0.69
HDAC1 Q13547 1/20 0.69
NCOR2 Q9Y618 1/20 0.69
PRMT1 Q99873 2/20 0.68
SETD7 Q8WTS6 1/20 0.65
PTGS1 P23219 2/20 0.64
SIRT1 Q96EB6 1/20 0.63
NPC1 O15118 1/20 0.63
RAB9A P51151 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Phenylbenzamide SCHEMBL27722554 0.96 MEN1 (0.74) POLBMEN1KMT2ALMNAPKM
SCHEMBL13335896 0.93 POLB (0.76) POLBMEN1KMT2ALMNAPKM
SCHEMBL158771 0.92 MEN1 (0.81) POLBMEN1KMT2ALMNAPKM
Hydrochloric Acid SCHEMBL18953624 0.90 MEN1 (0.78) POLBMEN1KMT2ALMNAPKM
Ammonia Solution, Strong SCHEMBL8043061 0.90 MEN1 (0.78) POLBMEN1KMT2ALMNAPKM
Bicarbonate SCHEMBL11209083 0.90 POLB (0.92) POLBMEN1KMT2ALMNAPKM
SCHEMBL28850376 0.90 PGR (0.71) POLBMEN1KMT2ALMNAPKM
SCHEMBL30319980 0.90 POLB (1.00) POLBMEN1KMT2ALMNAPKM
SCHEMBL137276 0.90 POLB (1.00) POLBMEN1KMT2ALMNAPKM
SCHEMBL9681496 0.90 POLB (1.00) POLBMEN1KMT2ALMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 376 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113185759-B Rubber containing modified graphene 福建师范大学泉港石化研究院 2022-04-01 CN claimed
EP-3668958-B1 NITROGEN-FUNCTIONALIZED OLEFIN POLYMERS FOR DRIVELINE LUBRICANTS LUBRIZOL CORP (US) 2022-02-02 EP claimed
EP-3913040-A1 DRIVELINE LUBRICANTS COMPRISING NITROGEN-FUNCTIONALIZED OLEFIN POLYMERS The Lubrizol Corporation (US) 2021-11-24 EP claimed
CN-113185759-A Rubber containing modified graphene 福建师范大学泉港石化研究院 2021-07-30 CN claimed
US-20210130732-A1 Nitrogen-Functionalized Olefin Polymers for Driveline Lubricants LUBRIZOL CORP (US) 2021-05-06 US claimed
US-10780400-B2 Agent, liquid, and method for cleaning reverse osmosis membrane KURITA WATER INDUSTRIES LTD. (JP) 2020-09-22 US claimed
CN-111133085-A Nitrogen functionalized olefin polymers for driveline lubricants 路博润公司 2020-05-08 CN claimed
US-7635662-B2 Compound for color-producing composition, and recording material CHEMIPRO KASEI KAISHA, LTD. (JP) 2009-12-22 US claimed
US-20060110743-A1 Drug evolution: drug design at hot spots KONISHI YASUO 2006-05-25 US claimed
WO-2002095393-A2 DRUG EVOLUTION: DRUG DESIGN AT HOT SPOTS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2002-11-28 WO claimed
EP-0475238-A2 Mesogenic glycidyl esters THE DOW CHEMICAL COMPANY (US) 1992-03-18 EP claimed
EP-0473935-A2 Curable mixture of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1992-03-11 EP claimed
EP-0213572-B1 3-AND 4-AMINO-N(ALKYL PHENYL) BENZAMIDE COMPOUNDS AND COMPOSITION CONTAINING SAME AS ANTICONVULSANT DRUGS Research Corporation Technologies, Inc. (a Delaware corp.) (US) 1991-07-03 EP claimed
EP-0213572-A1 3-and 4-amino-N(alkyl phenyl) benzamide compounds and composition containing same as anticonvulsant drugs Research Corporation Technologies, Inc. (a Delaware corp.) (US) 1987-03-11 EP claimed
EP-0078845-B1 ANTI-CONVULSANT CLARK, Charles Randall (US) 1987-02-04 EP claimed
US-4638014-A AMINOBENZANILIDES RESEARCH CORPORATION (US) 1987-01-20 US claimed
EP-0078845-A4 ANTI-CONVULSANT. CLARK CHARLES RANDALL 1983-09-02 EP claimed
EP-0078845-A1 ANTI-CONVULSANT. CLARK CHARLES RANDALL 1983-05-18 EP claimed
US-4379165-A Anti-convulsant RESEARCH CORPORATION (US) 1983-04-05 US claimed
WO-1982004046-A1 ANTI-CONVULSANT CLARK CHARLES RANDALL 1982-11-25 WO claimed