SCHEMBL158771

SCHEMBL158771

Nc1ccc(NC(=O)c2ccccc2)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.81
POLB P06746 2/20 0.81
KMT2A Q03164 2/20 0.81
LMNA P02545 1/20 0.81
PKM P14618 1/20 0.81
APEX1 P27695 1/20 0.81
TDP1 Q9NUW8 1/20 0.81
PRMT1 Q99873 3/20 0.78
PTPN1 P18031 2/20 0.71
NPC1 O15118 4/20 0.69
RAB9A P51151 4/20 0.69
SIRT1 Q96EB6 1/20 0.69
KDM4E B2RXH2 1/20 0.69
MAPT P10636 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
SETD7 Q8WTS6 1/20 0.65
CACNA1B Q00975 1/20 0.65
APBA1 Q02410 1/20 0.65
PTGS1 P23219 2/20 0.64
CA12 O43570 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL8043061 0.98 MEN1 (0.78) MEN1POLBKMT2ALMNAPKM
Hydrochloric Acid SCHEMBL18953624 0.98 MEN1 (0.78) MEN1POLBKMT2ALMNAPKM
N-Phenylbenzamide SCHEMBL27722554 0.96 MEN1 (0.74) MEN1POLBKMT2ALMNAPKM
SCHEMBL641853 0.92 POLB (0.81) MEN1POLBKMT2ALMNAPKM
Bicarbonate SCHEMBL11209083 0.90 POLB (0.92) MEN1POLBKMT2ALMNAPKM
SCHEMBL2285472 0.90 PRMT1 (0.66) MEN1POLBKMT2ALMNAPKM
SCHEMBL10448340 0.90 PRMT1 (0.66) MEN1POLBKMT2ALMNAPKM
SCHEMBL11650148 0.90 PGR (0.81) MEN1POLBKMT2ALMNAPKM
SCHEMBL2285475 0.90 PRMT1 (0.66) MEN1POLBKMT2ALMNAPKM
SCHEMBL1353478 0.90 POLB (1.00) MEN1POLBKMT2ALMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 692 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117820129-B Method for preparing corresponding aromatic amine by selective hydrogenation of photocatalytic aromatic nitro compound 南京先进生物材料与过程装备研究院有限公司 2024-09-06 CN claimed
CN-117820129-A Method for preparing corresponding aromatic amine by selective hydrogenation of photocatalytic aromatic nitro compound 南京先进生物材料与过程装备研究院有限公司 2024-04-05 CN claimed
CN-116288434-A Potential-regulated electrocatalytic unsaturated nitro compound controllable stepwise reduction method 大连理工大学 2023-06-23 CN claimed
EP-4077601-A1 POLYMERIC SURFACTANT COMPOUND The Lubrizol Corporation (US) 2022-10-26 EP claimed
CN-114829556-A Polymeric surfactant compounds 路博润公司 2022-07-29 CN claimed
WO-2021127183-A1 POLYMERIC SURFACTANT COMPOUND THE LUBRIZOL CORPORATION (US) 2021-06-24 WO claimed
CN-112409595-A Polyimide film and preparation method thereof 广东工业大学 2021-02-26 CN claimed
US-10780400-B2 Agent, liquid, and method for cleaning reverse osmosis membrane KURITA WATER INDUSTRIES LTD. (JP) 2020-09-22 US claimed
US-20200231550-A1 COMPOUNDS FOR TREATING TUBERCULOSIS NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2020-07-23 US claimed
CN-107383872-B Polypyromellitic-acyl p-phenylenediamine/carbon cloth material and preparation method and application thereof 华南理工大学 2020-02-18 CN claimed
CN-1990545-A Polyester composite material and method for preparing same SHANGHAI GENIUS ADVANCED MAT (CN) 2007-07-04 CN claimed
EP-1730202-A2 DISPERSANT VISCOSITY MODIFIERS BASED ON DIENE-CONTAINING POLYMERS The Lubrizol Corporation (US) 2006-12-13 EP claimed
WO-2005087821-A2 DISPERSANT VISCOSITY MODIFIERS BASED ON DIENE-CONTAINING POLYMERS THE LUBRIZOL CORPORATION (US) 2005-09-22 WO claimed
CN-1155278-A Arylthio compounds as antibacteral and antiviral agents WARNER LAMBERT CO (US) 1997-07-23 CN claimed
EP-0582677-B1 CYCLIC AROMATIC AMIDE OLIGOMERS DU PONT (US) 1997-06-18 EP claimed
US-5332800-A Cyclic aromatic amide oligomers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-07-26 US claimed
EP-0582677-A1 CYCLIC AROMATIC AMIDE OLIGOMERS. DU PONT (US) 1994-02-16 EP claimed
WO-1992019665-A1 CYCLIC AROMATIC AMIDE OLIGOMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-11-12 WO claimed
CN-1018900-B MOLDING METHOD THREE D COMPOSITE CO LTD (GB) 1992-11-04 CN claimed
CN-1031046-A Method of moulding 3 D COMPOSITES LTD (GB) 1989-02-15 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200231550-A1 COMPOUNDS FOR TREATING TUBERCULOSIS ATP5ME, ATP5MG, ATP5F1D MEN1 4589/4885POLB 327/4885KMT2A 2920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.