Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6421359 | 0.87 | ABCG2 (0.61) | ABCG2KDM4EALDH1A1LMNAGABRP | |
| SCHEMBL6418574 | 0.84 | ALDH1A1 (0.37) | ABCG2KDM4EALDH1A1LMNAGABRP | |
| SCHEMBL8001501 | 0.79 | TERT (0.37) | TOP1CYCS | |
| SCHEMBL6439541 | 0.77 | ABCG2 (0.51) | ABCG2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7704554 | 0.75 | ABCG2 (0.49) | ABCG2KDM4EALDH1A1LMNAGABRP | |
| SCHEMBL6418036 | 0.74 | NPC1 (0.49) | ABCG2KDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL6412627 | 0.74 | NPC1 (0.49) | ABCG2KDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL6412535 | 0.71 | ABCG2 (0.45) | ABCG2KDM4EALDH1A1LMNAHTT | |
| SCHEMBL6416109 | 0.71 | GAA (0.48) | ABCG2KDM4EALDH1A1LMNAHTT | |
| SCHEMBL6413587 | 0.69 | ABCG2 (0.43) | ABCG2KDM4EALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071474-B1 | SUBSTITUTED PORPHYRINS | UNIV DUKE (US) | 2005-11-30 | — | — | EP | disclosed |
| US-6479477-B1 | SUITABLE FOR USE IN MODULATING INTRA- AND EXTRACELLULAR PROCESSES IN WHICH SUPEROXIDE RADICALS, OR OTHER OXIDANTS SUCH AS HYDROGEN PEROXIDE OR PEROXYNITRITE, ARE A PARTICIPANT | DUKE UNIVERSITY | 2002-11-12 | — | — | US | disclosed |
| EP-1071474-A4 | SUBSTITUTED PORPHYRINS | UNIV DUKE (US) | 2002-10-24 | — | — | EP | disclosed |
| EP-1071474-A1 | SUBSTITUTED PORPHYRINS | DUKE UNIVERSITY (US) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999055388-A9 | SUBSTITUTED PORPHYRINS | UNIV DUKE (US) | 2000-01-27 | — | — | WO | disclosed |
| WO-1999055388-A1 | SUBSTITUTED PORPHYRINS | DUKE UNIVERSITY (US) | 1999-11-04 | — | — | WO | disclosed |