SCHEMBL641899

SCHEMBL641899

O=C(O)c1c2ccccc2nc2ccccc12

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 3/20 0.66
ALDH1A1 P00352 4/20 0.61
KDM4E B2RXH2 4/20 0.61
KMT2A Q03164 3/20 0.61
GLA P06280 3/20 0.61
MEN1 O00255 2/20 0.61
CYP2C19 P33261 2/20 0.61
HPGD P15428 2/20 0.61
HSD17B10 Q99714 2/20 0.61
CYP1A2 P05177 1/20 0.61
DHODH Q02127 5/20 0.61
LMNA P02545 1/20 0.61
TSHR P16473 1/20 0.59
CYP2D6 P10635 1/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
MAPT P10636 1/20 0.54
CDC7 O00311 1/20 0.50
EEF2K O00418 1/20 0.50
PLK4 O00444 1/20 0.50
DYRK3 O43781 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29377848 1.00 PDE10A (0.66) PDE10AALDH1A1KDM4EKMT2AGLA
Iodide SCHEMBL8029606 0.98 PDE10A (0.63) PDE10AALDH1A1KDM4EKMT2AGLA
Water SCHEMBL2991911 0.98 PDE10A (0.63) PDE10AALDH1A1KDM4EKMT2AGLA
Iodide SCHEMBL8029601 0.98 PDE10A (0.63) PDE10AALDH1A1KDM4EKMT2AGLA
Hydrochloric Acid SCHEMBL9597551 0.98 PDE10A (0.63) PDE10AALDH1A1KDM4EKMT2AGLA
Hydrochloric Acid SCHEMBL1603404 0.98 PDE10A (0.63) PDE10AALDH1A1KDM4EKMT2AGLA
SCHEMBL7516228 0.90 PDE10A (0.56) PDE10AALDH1A1KDM4EKMT2AGLA
SCHEMBL9056825 0.88 PDE10A (0.54) PDE10AALDH1A1KDM4EKMT2AGLA
SCHEMBL9056820 0.88 PDE10A (0.54) PDE10AALDH1A1KDM4EKMT2AGLA
SCHEMBL9330222 0.87 CYP2C19 (0.58) PDE10AALDH1A1KDM4EKMT2AGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 777 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4405369-A2 A CIS-PLATINUM(II)-OLIGOMER HYBRID Dublin City University (IE) 2024-07-31 EP claimed
CN-118103385-A Cis-platinum (II) oligomer hybrids 都柏林城市大学 2024-05-28 CN claimed
CN-117986188-A Preparation method of 9-alkenyl substituted acridine derivative 郑州原理生物科技有限公司 2024-05-07 CN claimed
CN-116925042-A DMAE acridine ester and preparation method and application thereof 上海品峰医疗科技有限公司 2023-10-24 CN claimed
CN-116621811-A Synthesis method of acridine ester compound 深圳市亚辉龙生物科技股份有限公司 2023-08-22 CN claimed
CN-113620877-B Method for preparing 9-acridine formic acid by one-pot method 重庆医药高等专科学校 2023-04-21 CN claimed
WO-2023046875-A2 A CIS-PLATINUM(II)-OLIGOMER HYBRID DUBLIN CITY UNIVERSITY (IE) 2023-03-30 WO claimed
CN-111777556-B Method for preparing acridine 9-carboxylic acid by oxidation method 遂成药业股份有限公司 2022-08-19 CN claimed
CN-113620877-A Method for preparing 9-acridine formic acid by one-pot method 重庆医药高等专科学校 2021-11-09 CN claimed
CN-110240564-B Preparation method of 9-hydroxymethyl-9, 10-dihydroacridine 郑州原理生物科技有限公司 2020-12-22 CN claimed
US-6171520-B1 Reagents for labeling SH groups, process for the preparation of them and method for labeling with them SS PHARMACEUTICAL CO., LTD. (JP) 2001-01-09 US claimed
EP-1023634-A1 IMPROVED THERMOSETTING ANTI-REFLECTIVE COATINGS AT DEEP ULTRAVIOLET Brewer Science, Inc. (US) 2000-08-02 EP claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
US-5919599-A ACRYLIC GRAFT POLYMERS BREWER SCIENCE, INC. (US) 1999-07-06 US claimed
WO-1999017161-A1 IMPROVED THERMOSETTING ANTI-REFLECTIVE COATINGS AT DEEP ULTRAVIOLET BREWER SCIENCE, INC. (US) 1999-04-08 WO claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
EP-0844246-A1 REAGENTS FOR LABELING SH GROUPS, PROCESS FOR THE PREPARATION OF THEM, AND METHOD FOR LABELING WITH THEM SS Pharmaceutical Co., Ltd. (JP) 1998-05-27 EP claimed
US-5543524-A FORMING A SULFONAMIDE FROM AND AMINE AND A SULFONYL HALIDE AND AND ACYLATING WITH A CARBONYL HALIDE OF AN ACTIVATED ACRIDINE SALT ABBOTT LABORATORIES (US) 1996-08-06 US claimed
EP-0273115-B1 Chemiluminescent acridinium and phenanthridinium salts ABBOTT LAB (US) 1994-09-07 EP claimed