SCHEMBL7516228

SCHEMBL7516228

O=C(Cl)c1c2ccccc2nc2ccccc12.O=C(O)c1c2ccccc2nc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 3/20 0.56
DHODH Q02127 5/20 0.53
LMNA P02545 1/20 0.53
ALDH1A1 P00352 4/20 0.52
KDM4E B2RXH2 4/20 0.52
KMT2A Q03164 3/20 0.52
GLA P06280 3/20 0.52
MEN1 O00255 2/20 0.52
CYP2C19 P33261 2/20 0.52
HPGD P15428 2/20 0.52
CYP1A2 P05177 1/20 0.52
HSD17B10 Q99714 1/20 0.52
TSHR P16473 1/20 0.51
CYP2D6 P10635 1/20 0.47
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.45
MAPT P10636 1/20 0.45
GAA P10253 1/20 0.45
ATM Q13315 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL642681 0.94 MAOA (0.52) PDE10ADHODHLMNAALDH1A1KDM4E
SCHEMBL31026536 0.94 MAOA (0.52) PDE10ADHODHLMNAALDH1A1KDM4E
Hydrochloric Acid SCHEMBL5735696 0.92 PDE10A (0.50) PDE10ADHODHLMNAALDH1A1KDM4E
SCHEMBL29377848 0.90 PDE10A (0.66) PDE10ADHODHLMNAALDH1A1KDM4E
SCHEMBL641899 0.90 PDE10A (0.66) PDE10ADHODHLMNAALDH1A1KDM4E
Iodide SCHEMBL8029606 0.88 PDE10A (0.63) PDE10ADHODHLMNAALDH1A1KDM4E
Hydrochloric Acid SCHEMBL9597551 0.88 PDE10A (0.63) PDE10ADHODHLMNAALDH1A1KDM4E
Hydrochloric Acid SCHEMBL1603404 0.88 PDE10A (0.63) PDE10ADHODHLMNAALDH1A1KDM4E
Iodide SCHEMBL8029601 0.88 PDE10A (0.63) PDE10ADHODHLMNAALDH1A1KDM4E
Water SCHEMBL2991911 0.88 PDE10A (0.63) PDE10ADHODHLMNAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1242622-A2 MONITORING OLIGONUCLEOTIDE BINDING PROCESSES USING CHEMILUMINESCENCE QUENCHING Molecular Light Technology Research Limited (GB) 2002-09-25 EP disclosed
WO-2001042497-A9 MONITORING OLIGONUCLEOTIDE BINDING PROCESSES USING CHEMILUMINESCENCE QUENCHING MOLECULAR LIGHT TECH RES LTD (GB) 2002-06-06 WO disclosed
WO-2001042497-A2 MONITORING OLIGONUCLEOTIDE BINDING PROCESSES USING CHEMILUMINESCENCE QUENCHING MOLECULAR LIGHT TECHNOLOGY RESEARCH LIMITED (GB) 2001-06-14 WO disclosed