SCHEMBL641942

SCHEMBL641942

N=CNC(CCC(=O)O)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 7/20 0.55
NAALAD2 Q9Y3Q0 3/20 0.55
RIMKLA Q8IXN7 1/20 0.55
GGH Q92820 2/20 0.47
TET2 Q6N021 3/20 0.41
KDM4A O75164 2/20 0.41
KDM4C Q9H3R0 2/20 0.41
KDM2A Q9Y2K7 2/20 0.41
TET3 O43151 1/20 0.41
CYP1A2 P05177 2/20 0.40
GRM8 O00222 1/20 0.40
GRM6 O15303 1/20 0.40
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GSR P00390 1/20 0.40
GRIK1 P39086 1/20 0.40
GRM5 P41594 1/20 0.40
GRIA1 P42261 1/20 0.40
GRIA2 P42262 1/20 0.40
GRIA3 P42263 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL188480 1.00 FOLH1 (0.55) FOLH1NAALAD2RIMKLAGGHTET2
SCHEMBL29123177 1.00 FOLH1 (0.55) FOLH1NAALAD2RIMKLAGGHTET2
SCHEMBL2921881 0.84 KMT2A (0.45) FOLH1NAALAD2RIMKLA
SCHEMBL15935963 0.81 FOLH1 (0.57) FOLH1NAALAD2RIMKLAGGHTET2
SCHEMBL702004 0.81 FOLH1 (0.57) FOLH1NAALAD2RIMKLAGGHTET2
SCHEMBL702003 0.81 FOLH1 (0.57) FOLH1NAALAD2RIMKLAGGHTET2
SCHEMBL5089988 0.79 FOLH1 (0.55) FOLH1NAALAD2RIMKLAGGHTET2
SCHEMBL28883926 0.79 FOLH1 (0.55) FOLH1NAALAD2RIMKLAGGHTET2
SCHEMBL5089992 0.79 FOLH1 (0.55) FOLH1NAALAD2RIMKLAGGHTET2
SCHEMBL4406367 0.78 CA2 (0.41) FOLH1NAALAD2RIMKLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118489060-A Compositions and methods for diagnosing and treating chronic kidney disease 雀巢产品有限公司 2024-08-13 CN claimed
CN-117214314-A Organic acid content detection box and detection method 深圳爱湾智造科技有限公司 2023-12-12 CN claimed
EP-2940143-B1 Method for the production of l-amino acids using an alkaliphilic bacterium EVONIK OPERATIONS GMBH (DE) 2020-02-05 EP claimed
EP-3465213-A1 METABALOMICS AND VIRAL DIAGNOSTICS SUITE Excision Biotherapeutics, Inc. (US) 2019-04-10 EP claimed
WO-2017205460-A1 METABALOMICS AND VIRAL DIAGNOSTICS SUITE EXCISION BIOTHERAPEUTICS, INC. (US) 2017-11-30 WO claimed
US-20170051323-A1 Method for Producing L-Amino Acids Using an Alkaliphilic Bacteria EVONIK DEGUSSA GMBH (DE) 2017-02-23 US claimed
CN-119343061-A Pharmaceutical and nutraceutical compositions containing amino acid combinations and their use in diseases characterized by lipid accumulation in tissues 欧罗卡特基金会 2025-01-21 CN disclosed
CN-118489060-A Compositions and methods for diagnosing and treating chronic kidney disease 雀巢产品有限公司 2024-08-13 CN disclosed
US-20240127925-A1 METHOD AND SYSTEM FOR DESIGNING PERSONALIZED THERAPEUTICS AND DIET BASED ON FUNCTIONS OF MICROBIOME TATA CONSULTANCY SERVICES LIMITED (IN) 2024-04-18 US disclosed
EP-4288559-A1 METHOD AND SYSTEM FOR DESIGNING PERSONALIZED THERAPEUTICS AND DIET BASED ON FUNCTIONS OF MICROBIOME Tata Consultancy Services Limited (IN) 2023-12-13 EP disclosed
CN-113793646-B Spectral image unmixing method based on weighted non-negative matrix factorization and application thereof 上海交通大学 2023-11-28 CN disclosed
US-11618880-B2 Compositions comprising bacterial strains and use thereof in controlling pathogenic microorganisms BETTER AIR INTERNATIONAL LIMITED (HK) 2023-04-04 US disclosed
WO-2022154182-A1 NOVEL FORMIMIDOYLGLUTAMASE VARIANT, AND METHOD FOR PRODUCING IMP USING SAME 씨제이제일제당 (주) 2022-07-21 WO disclosed
US-20080096253-A1 Artificial ribosome for use as synthesis structure during in vitro translation SUNGUROFF ALEXANDER 2008-04-24 US disclosed
EP-1642109-A4 METHODS FOR CONDUCTING ASSAYS FOR ENZYME ACTIVITY ON PROTEIN MICROARRAYS PROTOMETRIX INC (US) 2007-09-05 EP disclosed
US-20070178100-A1 Trypanosoma cruzi proteome compositions and methods GEORGIA RESEARCH FOUNDATION, INC., UNIVERSITY OF 2007-08-02 US disclosed
EP-1642109-A2 METHODS FOR CONDUCTING ASSAYS FOR ENZYME ACTIVITY ON PROTEIN MICROARRAYS Protometrix, Inc. (US) 2006-04-05 EP disclosed
WO-2005049642-A2 GENOME OF LEGIONELLA PNEUMOPHILA PARIS AND LENS STRAIN-DIAGNOSTIC AND EPIDEMIOLOGICAL APPLICATIONS INSTITUT PASTEUR (FR) 2005-06-02 WO disclosed
US-20050118665-A1 Methods for conducting assays for enzyme activity on protein microarrays PROTOMETRIX, INC. 2005-06-02 US disclosed
WO-2005003721-A2 ENZYME ACTIVITY ASSAYS ON PROTEIN MICROARRAYS PROTOMETRIX, INC. (US) 2005-01-13 WO disclosed