Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28361084 | 0.83 | THRB (0.40) | ALDH1A1TSHRTHRB | |
| SCHEMBL20578328 | 0.81 | FFAR3 (0.35) | ALDH1A1THRB | |
| SCHEMBL28357452 | 0.80 | ALDH1A1 (0.35) | ALDH1A1TSHRTHRB | |
| SCHEMBL18556467 | 0.79 | ALDH1A1 (0.30) | ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL2277689 | 0.79 | FFAR3 (0.33) | — | |
| Phosphine SCHEMBL10644934 | 0.79 | FFAR3 (0.33) | — | |
| SCHEMBL6420646 | 0.73 | ALDH1A1 (0.35) | ALDH1A1TSHRHTT | |
| SCHEMBL7990083 | 0.73 | GAA (0.38) | ALDH1A1TSHR | |
| SCHEMBL9541542 | 0.73 | HTT (0.37) | ALDH1A1TSHRHTTTHRB | |
| SCHEMBL10179585 | 0.71 | THRB (0.32) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1523490-A1 | METHOD FOR INTRODUCING A 1,2 DOUBLE BOND INTO 3-OXO-4-AZASTEROID COMPOUNDS | Siegfried Generics International AG (CH) | 2005-04-20 | — | — | EP | disclosed |
| WO-2004007523-A1 | METHOD FOR INTRODUCING A 1,2 DOUBLE BOND INTO 3-OXO-4-AZASTEROID COMPOUNDS | SIEGFRIED GENERICS INTERNATIONAL AG (CH) | 2004-01-22 | — | — | WO | disclosed |