Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18930074 | 0.74 | HTR2A (0.41) | HTR2AKDM4ECYP2D6HSD17B10TP53 | |
| SCHEMBL7869538 | 0.72 | HTR2A (0.50) | HTR2AKDM4ECYP2D6HSD17B10TP53 | |
| SCHEMBL8036851 | 0.72 | HTR2A (0.50) | HTR2AKDM4ECYP2D6HSD17B10TP53 | |
| SCHEMBL10080430 | 0.72 | HTR2A (0.56) | HTR2AKDM4ECYP2D6HSD17B10TP53 | |
| SCHEMBL11875463 | 0.72 | BRD4 (0.53) | HTR2AKDM4ECYP2D6HSD17B10TP53 | |
| SCHEMBL1276091 | 0.72 | HTR2A (0.50) | HTR2AKDM4ECYP2D6HSD17B10TP53 | |
| SCHEMBL5679950 | 0.72 | HTR2A (0.50) | HTR2AKDM4ECYP2D6HSD17B10TP53 | |
| SCHEMBL31099344 | 0.72 | HTR2A (0.50) | HTR2AKDM4ECYP2D6HSD17B10TP53 | |
| SCHEMBL4108490 | 0.71 | GPR3 (0.46) | HTR2ACYP2D6CHRM2CHRM1SLC6A2 | |
| SCHEMBL24475199 | 0.70 | MEN1 (0.33) | HTR2AMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107608-A1 | Ligands for use in catalytic processes | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH ETHZ (CH) | 2005-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107608-A1 | Ligands for use in catalytic processes | PNKP, ITPA, PLCG2 | HTR2A 4161/4885KDM4E 3430/4885CYP2D6 1296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.