Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24473932 | 0.82 | GPR3 (0.34) | GPR3HTR2AACHEBCHEHDAC3 | |
| SCHEMBL524603 | 0.73 | GPR3 (0.50) | GPR3HTR2AACHEBCHEHDAC3 | |
| SCHEMBL29950614 | 0.73 | GPR3 (0.50) | GPR3HTR2AACHEBCHEHDAC3 | |
| SCHEMBL1107108 | 0.71 | GPR3 (0.48) | GPR3HTR2AACHEBCHEHDAC3 | |
| SCHEMBL825558 | 0.71 | HTR2A (0.55) | GPR3HTR2AACHEBCHEHDAC3 | |
| Hydrochloric Acid SCHEMBL9054770 | 0.71 | GPR3 (0.42) | GPR3HTR2AACHEBCHEHDAC3 | |
| SCHEMBL6420010 | 0.71 | HTR2A (0.50) | HTR2AACHEBCHEPOLBCYP2D6 | |
| SCHEMBL11302125 | 0.69 | MAOA (0.58) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL1766205 | 0.69 | GPR3 (0.46) | GPR3HTR2AACHEBCHEHDAC3 | |
| SCHEMBL40599 | 0.69 | GPR3 (0.52) | GPR3HTR2AACHEBCHEHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253907-A1 | CYCLOPENTADIENYL, INDENYL OR FLUORENYL SUBSTITUTED PHOSPHINE COMPOUNDS AND THEIR USE IN CATALYTIC REACTIONS | EVONIK DEGUSSA GMBH (DE) | 2009-10-08 | — | — | US | claimed |
| EP-1894938-A1 | New cyclopentadienyl, indenyl or fluorenyl substituted phosphine compounds and their use in catalytic reactions | Evonik Degussa GmbH (DE) | 2008-03-05 | — | — | EP | claimed |
| US-12043680-B2 | Ethylene and isoprene copolymer | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2024-07-23 | — | — | US | disclosed |
| US-12043680-B2 | Ethylene and isoprene copolymer | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2024-07-23 | — | — | US | disclosed |
| US-20240218104-A1 | FUNCTIONAL COPOLYMER OF A 1,3-DIENE AND ETHYLENE OR A 1,3-DIENE, ETHYLENE AND AN ALPHA-MONOOLEFIN | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2024-07-04 | — | — | US | disclosed |
| US-20240218104-A1 | FUNCTIONAL COPOLYMER OF A 1,3-DIENE AND ETHYLENE OR A 1,3-DIENE, ETHYLENE AND AN ALPHA-MONOOLEFIN | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2024-07-04 | — | — | US | disclosed |
| US-20240026058-A1 | SYNTHESIS OF BLOCK POLYMERS BASED ON 1,3-DIENE AND ETHYLENE | UNIVERSITÉ CLAUDE BERNARD LYON 1 (FR) | 2024-01-25 | — | — | US | disclosed |
| US-20240026058-A1 | SYNTHESIS OF BLOCK POLYMERS BASED ON 1,3-DIENE AND ETHYLENE | UNIVERSITÉ CLAUDE BERNARD LYON 1 (FR) | 2024-01-25 | — | — | US | disclosed |
| WO-2023237380-A1 | COUPLED POLYETHYLENES OR COPOLYMERS OF ETHYLENE AND 1,3-DIENE, AND PROCESS FOR THE PREPARATION THEREOF | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023237381-A1 | PROCESS FOR THE SYNTHESIS OF POLYETHYLENES OR COPOLYMERS OF ETHYLENE AND 1,3-DIENE HAVING A TERMINAL KETONE FUNCTION | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2023-12-14 | — | — | WO | disclosed |
| US-20230357462-A1 | CATALYTIC SYSTEM BASED ON A METALLOCENE AND A DIORGANOMAGNESIUM | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2023-11-09 | — | — | US | disclosed |
| US-20040256616-A1 | Process of preparing a disubstituted 9-alkylidenefluorene or a derivative thereof | MERCK PATENT GMBH (DE) | 2004-12-23 | — | — | US | disclosed |
| EP-1468988-A1 | Process of preparing disubstituted 9-alkylidenefluorenes and derivatives thereof | MERCK PATENT GmbH (DE) | 2004-10-20 | — | — | EP | disclosed |
| EP-0442638-B1 | Polymeric compounds | DU PONT UK (GB) | 1996-07-10 | — | — | EP | disclosed |
| US-5278022-A | Photopolymerizable | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-01-11 | — | — | US | disclosed |
| EP-0358400-B1 | Improvements in or relating to polymeric compounds | DU PONT (US) | 1993-11-10 | — | — | EP | disclosed |
| US-5162431-A | Photosensitive Binders | DU PONT-HOWSON LIMITED (GB) | 1992-11-10 | — | — | US | disclosed |
| US-5120799-A | POLYMERIC COMPOUNDS HAVING PENDANT SULPHONATO GROUPS AND METHOD OF PRODUCING THE POLYMERIC COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (INC.) (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0442638-A2 | Polymeric compounds | Du Pont (UK) Limited (GB) | 1991-08-21 | — | — | EP | disclosed |
| EP-0358400-A2 | Improvements in or relating to polymeric compounds | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357462-A1 | CATALYTIC SYSTEM BASED ON A METALLOCENE AND A DIORGANOMAGNESIUM | REL, DNMT1, MED16 | GPR3 2068/4885HTR2A 4747/4885ACHE 27/4885 |
| US-20090253907-A1 | CYCLOPENTADIENYL, INDENYL OR FLUORENYL SUBSTITUTED PHOSPHINE COMPOUNDS AND THEIR USE IN CATALYTIC REACTIONS | CPS1, CYCS, RRS1 | GPR3 669/4885HTR2A 3916/4885ACHE 3578/4885 |
| US-20040256616-A1 | Process of preparing a disubstituted 9-alkylidenefluorene or a derivative thereof | PFAS, FDPS, ALG8 | GPR3 4341/4885HTR2A 3442/4885ACHE 4326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.