Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 4/20 | 0.34 |
| ▸ | CDK1 | P06493 | 3/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.31 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11516141 | 0.73 | RAB9A (0.49) | RAB9ALMNAALDH1A1POLB | |
| SCHEMBL8819209 | 0.72 | RAB9A (0.46) | RAB9ALMNAALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL7528704 | 0.69 | RAB9A (0.58) | RAB9ALMNAALDH1A1POLB | |
| SCHEMBL4004258 | 0.66 | RAB9A (0.56) | RAB9ALMNAALDH1A1POLB | |
| SCHEMBL4762153 | 0.66 | RAB9A (0.51) | RAB9ALMNAALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL7529821 | 0.65 | RAB9A (0.54) | RAB9ALMNAALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL16038162 | 0.65 | RAB9A (0.50) | RAB9ALMNAALDH1A1POLB | |
| SCHEMBL3441643 | 0.62 | RAB9A (1.00) | RAB9ALMNAALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL1978418 | 0.62 | RAB9A (0.50) | RAB9ALMNAALDH1A1POLB | |
| SCHEMBL6846885 | 0.62 | RAB9A (0.36) | RAB9ALMNAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908926-B1 | Substituted imidazoles, their preparation and use | NOVO NORDISK A/S (DK) | 2005-06-21 | — | — | US | disclosed |
| EP-1173438-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000063208-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-10-26 | — | — | WO | disclosed |