Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 3/20 | 0.60 |
| ▸ | TUBB | P07437 | 3/20 | 0.60 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.60 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.60 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.60 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.60 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.60 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.60 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.60 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.60 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.60 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.60 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.60 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.60 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.60 |
| ▸ | MYB | P10242 | 13/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5959431 | 0.81 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4326758 | 0.81 | TUBB4A (0.69) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6640779 | 0.80 | TUBB4A (0.61) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5729902 | 0.80 | TUBB4A (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5959313 | 0.80 | TUBB4A (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Crolibulin SCHEMBL1750915 | 0.80 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Crolibulin SCHEMBL1750454 | 0.80 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Crolibulin SCHEMBL29385790 | 0.80 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Crolibulin SCHEMBL29453293 | 0.80 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Crolibulin SCHEMBL1750575 | 0.80 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230232-B1 | SUBSTITUTED 4H-CHROMENE AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA INC (US) | 2004-02-25 | — | — | EP | claimed |
| US-6906203-B1 | Substituted 4H-chromene and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. (US) | 2005-06-14 | — | — | US | disclosed |