Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 3/20 | 0.61 |
| ▸ | TUBB | P07437 | 3/20 | 0.61 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.61 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.61 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.61 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.61 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.61 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.61 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.61 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.61 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.61 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.61 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.61 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.61 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.61 |
| ▸ | MYB | P10242 | 13/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6638623 | 0.94 | MYB (0.60) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6640084 | 0.85 | MYB (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6637510 | 0.84 | MYB (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6641362 | 0.83 | HSD17B10 (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5959431 | 0.80 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Crolibulin SCHEMBL29385790 | 0.80 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Crolibulin SCHEMBL1750454 | 0.80 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Crolibulin SCHEMBL1750915 | 0.80 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Crolibulin SCHEMBL29453293 | 0.80 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL19732221 | 0.80 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230232-B1 | SUBSTITUTED 4H-CHROMENE AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA INC (US) | 2004-02-25 | — | — | EP | claimed |