Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 2/20 | 0.67 |
| ▸ | TUBB | P07437 | 2/20 | 0.67 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.67 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.67 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.67 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.67 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.67 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.67 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.67 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.67 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.67 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.67 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.67 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.67 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 13/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | LMNA | P02545 | 5/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4332534 | 0.91 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30628020 | 0.89 | MEN1 (0.73) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4326115 | 0.89 | MEN1 (0.73) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4333403 | 0.89 | MEN1 (0.67) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28927732 | 0.87 | MEN1 (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30628022 | 0.87 | POLB (0.73) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30628023 | 0.87 | MEN1 (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28644827 | 0.87 | POLB (0.73) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4331808 | 0.87 | ALDH1A1 (0.65) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4319250 | 0.87 | MEN1 (0.76) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113620919-B | Mechanical ball milling assisted synthesis method of 2-amino-3-cyano-4H-pyran compound | 浙江工业大学 | 2023-12-12 | — | — | CN | disclosed |
| CN-113620919-A | Mechanical ball-milling auxiliary synthesis method of 2-amino-3-cyano-4H-pyran compounds | 浙江工业大学 | 2021-11-09 | — | — | CN | disclosed |
| US-6906203-B1 | Substituted 4H-chromene and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. (US) | 2005-06-14 | — | — | US | disclosed |