Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | SDHB | P21912 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6414145 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL5207573 | 0.76 | SMN1; SMN2 (1.00) | SMN1; SMN2CCNE2CCNE1CDK2KDM4E | |
| SCHEMBL219145 | 0.71 | ALDH1A1 (0.44) | SMN1; SMN2KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL6414035 | 0.67 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL1143192 | 0.67 | SMN1; SMN2 (0.58) | SMN1; SMN2CCNE2CCNE1CDK2KDM4E | |
| SCHEMBL6412005 | 0.67 | SMN1; SMN2 (0.58) | SMN1; SMN2CCNE2CCNE1CDK2KDM4E | |
| SCHEMBL624712 | 0.67 | SMN1; SMN2 (0.54) | SMN1; SMN2CCNE2CCNE1CDK2KDM4E | |
| SCHEMBL14400727 | 0.67 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4EALDH1A1GAAADORA2A | |
| SCHEMBL1074425 | 0.67 | SMPD3 (0.38) | SMN1; SMN2SMPD3KDM4EALDH1A1GAA | |
| SCHEMBL24177588 | 0.65 | KMT2A (0.46) | SMPD3KDM4EALDH1A1L3MBTL1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050048092-A1 | Thienyl-pyrazoles and their use for controlling pests | WADA KATSUAKI (JP) | 2005-03-03 | — | — | US | disclosed |
| US-6593358-B1 | Method for controlling pests, comprising the step of allowing a pesticidally effective amount of one or more compounds selected from the group consisting of one or more compounds of the formula (Ia) according to claim 2 and one or compounds | NIHON BAYER AGROCHEM K.K. (JP) | 2003-07-15 | — | — | US | disclosed |
| EP-1200425-A1 | THIENYL-PYRAZOLES AND THEIR USE FOR CONTROLLING PESTS | NIHON BAYER AGROCHEM K.K. (JP) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001005787-A1 | THIENYL-PYRAZOLES AND THEIR USE FOR CONTROLLING PESTS | NIHON BAYER AGROCHEM K.K. (DE) | 2001-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050048092-A1 | Thienyl-pyrazoles and their use for controlling pests | CBR3, C1S, CYP4B1 | SMN1; SMN2 4328/4885CCNE2 666/4885CCNE1 460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.