Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3441643 | 0.80 | RAB9A (1.00) | LMNAALDH1A1RAB9APOLBKDM4E | |
| SCHEMBL4357488 | 0.79 | RAB9A (0.74) | LMNAALDH1A1RAB9APOLBKDM4E | |
| Hydrochloric Acid SCHEMBL7526788 | 0.79 | RAB9A (0.97) | LMNAALDH1A1RAB9APOLBKDM4E | |
| SCHEMBL1977154 | 0.72 | RAB9A (0.51) | LMNAALDH1A1RAB9APOLBAOC3 | |
| Hydrochloric Acid SCHEMBL11516807 | 0.71 | RAB9A (0.50) | LMNAALDH1A1RAB9APOLBAOC3 | |
| Hydrochloric Acid SCHEMBL1978418 | 0.71 | RAB9A (0.50) | LMNAALDH1A1RAB9APOLBAOC3 | |
| SCHEMBL4004258 | 0.70 | RAB9A (0.56) | LMNAALDH1A1RAB9APOLBKDM4E | |
| Hydrochloric Acid SCHEMBL7529821 | 0.68 | RAB9A (0.54) | LMNAALDH1A1RAB9APOLBKDM4E | |
| SCHEMBL1991375 | 0.68 | RAB9A (0.66) | LMNAALDH1A1RAB9APOLBKDM4E | |
| Hydrochloric Acid SCHEMBL11515794 | 0.67 | RAB9A (0.64) | LMNAALDH1A1RAB9APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908926-B1 | Substituted imidazoles, their preparation and use | NOVO NORDISK A/S (DK) | 2005-06-21 | — | — | US | disclosed |
| EP-1173438-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000063208-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-10-26 | — | — | WO | disclosed |