Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 11/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.35 |
| ▸ | NPC1 | O15118 | 10/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.34 |
| ▸ | RELA | Q04206 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2956561 | 0.85 | MIF (0.59) | MIFGABRA1RAB9AALDH1A1NPC1 | |
| SCHEMBL2956514 | 0.81 | MIF (0.54) | MIFGABRA1RAB9AALDH1A1NPC1 | |
| SCHEMBL2962042 | 0.79 | GABRA1 (0.59) | MIFGABRA1RAB9AALDH1A1NPC1 | |
| SCHEMBL2957632 | 0.78 | MIF (0.57) | MIFGABRA1RAB9AALDH1A1NPC1 | |
| SCHEMBL2963185 | 0.77 | GABRA1 (0.56) | MIFGABRA1RAB9AALDH1A1NPC1 | |
| SCHEMBL2962338 | 0.75 | MIF (0.64) | MIFGABRA1RAB9AALDH1A1NPC1 | |
| SCHEMBL2959997 | 0.75 | GABRA1 (0.56) | MIFGABRA1RAB9AALDH1A1NPC1 | |
| SCHEMBL13217133 | 0.74 | MIF (0.56) | MIFGABRA1RAB9AALDH1A1NPC1 | |
| SCHEMBL2962217 | 0.74 | MIF (0.58) | MIFGABRA1RAB9AALDH1A1NPC1 | |
| SCHEMBL2955767 | 0.73 | MIF (0.54) | MIFGABRA1RAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050032786-A1 | 1, 3-benzothiazinone derivatives and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032786-A1 | 1, 3-benzothiazinone derivatives and use thereof | MIF, MORF4L1, FOXM1 | MIF 1/4885GABRA1 3323/4885RAB9A 4678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.