SCHEMBL6420409

SCHEMBL6420409

CC(C)(C)c1cc(Cc2ccccc2)cc(C(C)(C)C)c1O.CCCC(c1cc(C(C)(C)C)c(O)cc1C)(c1cc(C(C)(C)C)c(O)cc1C)c1cc(C(C)(C)C)c(O)cc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.41
ALOX15 P16050 3/20 0.41
CYP2C9 P11712 3/20 0.41
CYP2C19 P33261 3/20 0.41
CYP2D6 P10635 1/20 0.41
GAA P10253 3/20 0.40
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
HSPA5 P11021 1/20 0.36
SCN2A Q99250 2/20 0.35
BCL2 P10415 1/20 0.35
BCL2L1 Q07817 1/20 0.35
ALDH1A1 P00352 5/20 0.35
TSHR P16473 4/20 0.35
CYP3A4 P08684 3/20 0.35
LMNA P02545 2/20 0.35
MAPK1 P28482 2/20 0.35
HIF1A Q16665 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butylated Hydroxytoluene SCHEMBL8487462 0.82 ALDH1A1 (0.53) TP53ALOX15CYP2C9CYP2C19CYP2D6
SCHEMBL225503 0.82 ALOX15 (0.53) TP53ALOX15CYP2C9CYP2C19CYP2D6
SCHEMBL29498346 0.82 ALOX15 (0.53) TP53ALOX15CYP2C9CYP2C19CYP2D6
SCHEMBL1187217 0.79 MEN1 (0.57) TP53ALOX15CYP2C9CYP2C19CYP2D6
SCHEMBL5009340 0.76 CYP2C9 (0.50) TP53ALOX15CYP2C9CYP2C19CYP2D6
Diethyl Sulfide SCHEMBL28247409 0.74 MEN1 (0.49) TP53ALOX15CYP2C9CYP2C19CYP2D6
SCHEMBL11459104 0.73 ALOX15 (0.79) TP53ALOX15CYP2C9CYP2C19CYP2D6
Hypophosphorous Acid SCHEMBL10825638 0.72 MEN1 (0.51) TP53ALOX15CYP2C9CYP2C19CYP2D6
Benzene SCHEMBL9807217 0.72 ALDH1A1 (0.59) TP53ALOX15CYP2C9CYP2C19CYP2D6
Hypophosphorous Acid SCHEMBL6556020 0.72 GAA (0.54) TP53ALOX15CYP2C9CYP2C19CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1516634-A1 VOLATILIZER Earth Chemical Co., Ltd. (JP) 2005-03-23 EP disclosed