Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PAK4 | O96013 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7494120 | 0.72 | — | — | |
| SCHEMBL5750912 | 0.71 | HTR2C (0.49) | RAB9AALDH1A1KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL718221 | 0.71 | KDM4E (0.37) | ALDH1A1KDM4ESMN1; SMN2MAPK1KMT2A | |
| SCHEMBL11625717 | 0.68 | POLB (0.50) | POLBRAB9APLD1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29388549 | 0.67 | CDC7 (0.60) | POLBRAB9AALDH1A1PRKD3PRKACA | |
| SCHEMBL31107087 | 0.67 | CDC7 (0.60) | POLBRAB9AALDH1A1PRKD3PRKACA | |
| SCHEMBL524138 | 0.67 | CDC7 (0.60) | POLBRAB9AALDH1A1PRKD3PRKACA | |
| SCHEMBL7102988 | 0.67 | KAT2B (0.46) | POLBRAB9AALDH1A1GAAKDM4E | |
| SCHEMBL11504697 | 0.66 | MAOA (0.41) | POLBALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL31020506 | 0.66 | IRAK4 (0.57) | POLBRAB9AALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166058-A | Fluoro beta-carboline compounds | 奥斯特克有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-112996506-A | Pyrrolodipyridine compounds | 奥斯特克有限公司 | 2021-06-18 | — | — | CN | disclosed |
| EP-1534293-A1 | ANTI-INFLAMMATORY COMPOSITIONS AND METHODS OF USE | Chemocentryx, Inc. (US) | 2005-06-01 | — | — | EP | disclosed |
| WO-2003105857-A1 | ANTI-INFLAMMATORY COMPOSITIONS AND METHODS OF USE | CHEMOCENTRYX (US) | 2003-12-24 | — | — | WO | disclosed |