Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8385563 | 0.72 | TSHR (0.47) | TSHRTHRBALDH1A1SLC22A1TP53 | |
| SCHEMBL8383966 | 0.72 | TSHR (0.47) | TSHRTHRBALDH1A1SLC22A1TP53 | |
| SCHEMBL8385298 | 0.72 | TSHR (0.47) | TSHRTHRBALDH1A1SLC22A1TP53 | |
| SCHEMBL8380720 | 0.72 | TSHR (0.47) | TSHRTHRBALDH1A1SLC22A1TP53 | |
| SCHEMBL8382287 | 0.71 | TSHR (0.40) | TSHRTHRBALDH1A1SLC22A1TP53 | |
| SCHEMBL8384712 | 0.71 | TSHR (0.40) | TSHRTHRBALDH1A1SLC22A1TP53 | |
| SCHEMBL8380402 | 0.71 | TSHR (0.40) | TSHRTHRBALDH1A1SLC22A1TP53 | |
| SCHEMBL8385822 | 0.71 | TSHR (0.40) | TSHRTHRBALDH1A1SLC22A1TP53 | |
| SCHEMBL8381507 | 0.71 | TSHR (0.40) | TSHRTHRBALDH1A1SLC22A1TP53 | |
| SCHEMBL8385036 | 0.71 | TSHR (0.40) | TSHRTHRBALDH1A1SLC22A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6946537-B2 | Siloxane oligomers, a process for their production and their use | DEGUSSA AG (DE) | 2005-09-20 | — | — | US | disclosed |
| US-20040158090-A1 | Siloxane oligomers, a process for their production and their use | EVONIK DEGUSSA GMBH (DE) | 2004-08-12 | — | — | US | disclosed |
| US-20030018155-A1 | Siloxane oligomers, a process for their production and their use | DEGUSSA AG (DE) | 2003-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040158090-A1 | Siloxane oligomers, a process for their production and their use | SAAL1, RAD54L, RTF1 | TSHR 3723/4885THRB 1443/4885ALDH1A1 216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.