Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14654944 | 0.88 | EPHX1 (0.50) | EPHX1RAB9ANPC1PKMALDH1A1 | |
| SCHEMBL14654898 | 0.88 | EPHX1 (0.50) | EPHX1RAB9ANPC1PKMALDH1A1 | |
| SCHEMBL13246733 | 0.83 | EPHX1 (0.53) | EPHX1RAB9ANPC1PKMALDH1A1 | |
| SCHEMBL26140573 | 0.83 | EPHX1 (0.53) | EPHX1RAB9ANPC1PKMALDH1A1 | |
| SCHEMBL15906201 | 0.82 | EPHX1 (0.52) | EPHX1RAB9ANPC1PKMALDH1A1 | |
| Hydrochloric Acid SCHEMBL29904533 | 0.82 | EPHX1 (0.52) | EPHX1RAB9ANPC1PKMALDH1A1 | |
| SCHEMBL25676344 | 0.80 | EPHX1 (0.50) | EPHX1RAB9ANPC1PKMALDH1A1 | |
| SCHEMBL25676313 | 0.80 | EPHX1 (0.50) | EPHX1RAB9ANPC1PKMALDH1A1 | |
| SCHEMBL14655013 | 0.79 | EPHX1 (0.46) | EPHX1RAB9ANPC1PKMALDH1A1 | |
| SCHEMBL25068274 | 0.79 | PKM (0.47) | EPHX1RAB9ANPC1PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1742001-A | Saturated quinoxaline derivatives and their use as metabotropic glutamate receptor ligands | ASTRAZENECA AB (SE) | 2006-03-01 | — | — | CN | disclosed |
| US-20050004130-A1 | New metabotropic glutamate receptor compounds | ASTRAZENECA AND NPS PHARMACEUTICALS, INC. | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004130-A1 | New metabotropic glutamate receptor compounds | GRM1, GRIN1, GRM2 | EPHX1 1179/4885RAB9A 1927/4885NPC1 1341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.