Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29904533 | 0.98 | EPHX1 (0.52) | EPHX1ALDH1A1PKMPDK1PDK2 | |
| SCHEMBL4087474 | 0.91 | ALDH1A1 (0.60) | EPHX1ALDH1A1PKMPDK1PDK2 | |
| SCHEMBL21100016 | 0.91 | ALDH1A1 (0.60) | EPHX1ALDH1A1PKMPDK1PDK2 | |
| SCHEMBL15906201 | 0.85 | EPHX1 (0.52) | EPHX1ALDH1A1PKMPDK1PDK2 | |
| SCHEMBL14654898 | 0.83 | EPHX1 (0.50) | EPHX1ALDH1A1PKMPDK1PDK2 | |
| SCHEMBL6420804 | 0.83 | EPHX1 (0.50) | EPHX1ALDH1A1PKMPDK1PDK2 | |
| SCHEMBL14654944 | 0.83 | EPHX1 (0.50) | EPHX1ALDH1A1PKMPDK1PDK2 | |
| SCHEMBL23573489 | 0.83 | ALDH1A1 (0.53) | EPHX1ALDH1A1PKMPDK1PDK2 | |
| SCHEMBL15317763 | 0.83 | EPHX2 (0.58) | EPHX1ALDH1A1PKMPDK1PDK2 | |
| SCHEMBL17690659 | 0.83 | EPHX2 (0.58) | EPHX1ALDH1A1PKMPDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240190856-A1 | MELANOCORTIN-4 RECEPTOR AGONIST | LG CHEM, LTD. (KR) | 2024-06-13 | — | — | US | claimed |
| US-20240190856-A1 | MELANOCORTIN-4 RECEPTOR AGONIST | LG CHEM, LTD. (KR) | 2024-06-13 | — | — | US | disclosed |
| WO-2024108198-A2 | METHODS OF TREATING OBESITY WITH AN MC4R AGONIST | RHYTHM PHARMACEUTICALS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| WO-2022182194-A1 | MELANOCORTIN-4 RECEPTOR AGONIST | 주식회사 엘지화학 | 2022-09-01 | — | — | WO | disclosed |
| US-20150337013-A1 | NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS | MERCK SHARP & DOHME CORP. (US) | 2015-11-26 | — | — | US | disclosed |
| US-20140073558-A1 | NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS | CUBIST PHARMACEUTICALS, INC. (US) | 2014-03-13 | — | — | US | disclosed |
| US-8507647-B2 | Antibacterial agents for the treatment of gram positive infections | CUBIST PHARMACEUTICALS, INC. (US) | 2013-08-13 | — | — | US | disclosed |
| US-20100184649-A1 | NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS | CUBIST PHARMACEUTICALS, INC. | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150337013-A1 | NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS | CLPP, CLPTM1, RPN1 | EPHX1 3837/4885ALDH1A1 4703/4885PKM 4765/4885 |
| US-20100184649-A1 | NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS | CLPP, CLPTM1, RPN1 | EPHX1 3837/4885ALDH1A1 4703/4885PKM 4765/4885 |
| US-20240190856-A1 | MELANOCORTIN-4 RECEPTOR AGONIST | MC4R, MC5R, MC3R | EPHX1 1479/4885ALDH1A1 1216/4885PKM 2753/4885 |
| US-20140073558-A1 | NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS | CLPP, CLPTM1, RPN1 | EPHX1 3837/4885ALDH1A1 4703/4885PKM 4765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.