Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6421094 | 0.88 | PTGDR2 (0.59) | HDAC1HDAC6 | |
| SCHEMBL6421118 | 0.86 | HDAC1 (0.55) | HDAC1HDAC6 | |
| SCHEMBL6421798 | 0.86 | HDAC1 (0.55) | HDAC1HDAC6 | |
| SCHEMBL6423329 | 0.85 | HDAC1 (0.55) | HDAC1HDAC6 | |
| SCHEMBL9615138 | 0.84 | HDAC6 (0.64) | HDAC1HDAC6 | |
| SCHEMBL6420742 | 0.84 | HDAC1 (0.54) | HDAC1HDAC6 | |
| SCHEMBL6422016 | 0.84 | HDAC1 (0.54) | HDAC1HDAC6 | |
| SCHEMBL4185797 | 0.84 | HDAC1 (0.56) | HDAC1HDAC6 | |
| SCHEMBL6423858 | 0.83 | HDAC1 (0.53) | HDAC1HDAC6 | |
| SCHEMBL6424243 | 0.83 | HDAC1 (0.55) | HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057814-B1 | TETRAHYDROBENZINDOLE DERIVATIVES | MEIJI SEIKA KAISHA (JP) | 2005-03-09 | — | — | EP | disclosed |
| US-6498251-B1 | Tetrahydrobenzindole derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-12-24 | — | — | US | disclosed |
| EP-1057814-A1 | TETRAHYDROBENZINDOLE DERIVATIVES | Meiji Seika Kaisha, Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |
| US-6057311-A | TREATING EATING DISORDERS | JAMES BLACK FOUNDATION LIMITED (GB) | 2000-05-02 | — | — | US | disclosed |
| WO-1997032860-A1 | BENZODIAZONINE DERIVATIVES BINDING TO CHOLECYSTOKININ OR GASTRIN RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 1997-09-12 | — | — | WO | disclosed |