Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.98 |
| ▸ | DRD2 | P14416 | 4/20 | 0.68 |
| ▸ | DRD3 | P35462 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.64 |
| ▸ | RELA | Q04206 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 2/20 | 0.62 |
| ▸ | HTR7 | P34969 | 2/20 | 0.62 |
| ▸ | HRH1 | P35367 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5261357 | 0.99 | HRH3 (1.00) | HRH3DRD2DRD3KDM4ENPC1 | |
| SCHEMBL6421371 | 0.90 | HRH3 (0.84) | HRH3DRD2DRD3HTR1AHTR7 | |
| SCHEMBL6421366 | 0.86 | HRH3 (0.77) | HRH3DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL6421382 | 0.83 | HRH3 (0.73) | HRH3DRD2DRD3HTR1AHTR7 | |
| SCHEMBL4653816 | 0.83 | HRH3 (1.00) | HRH3DRD2DRD3 | |
| SCHEMBL6291771 | 0.83 | HRH3 (1.00) | HRH3DRD2DRD3 | |
| SCHEMBL5416238 | 0.82 | HRH3 (1.00) | HRH3DRD2DRD3KDM4ENPC1 | |
| SCHEMBL5257756 | 0.81 | HRH3 (1.00) | HRH3DRD2DRD3 | |
| SCHEMBL8086599 | 0.81 | DRD3 (1.00) | HRH3DRD2DRD3HTR1AHTR7 | |
| SCHEMBL19322156 | 0.81 | NPC1 (0.90) | HRH3DRD2DRD3KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908929-B2 | Phenyl-substituted imidazopyridines | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2005-06-21 | — | — | US | claimed |